Targiniq and Omeprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Targiniq (naloxone hydrochloride; oxycodone hydrochloride) and Omeprazole (omeprazole). Common drug interactions include hypotension among females and femur fracture among males.

The phase IV clinical study analyzes what interactions people have when they take Targiniq and Omeprazole. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Targiniq?

Targiniq has active ingredients of naloxone hydrochloride; oxycodone hydrochloride. eHealthMe is studying from 580 Targiniq users. Check the latest studies of Targiniq.

What is Omeprazole?

Omeprazole has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 410,631 Omeprazole users. Check the latest studies of Omeprazole.

On Jul, 08, 2026

46 people who take Targiniq and Omeprazole together, and have interactions are studied.

Targiniq and Omeprazole drug interactions.

What are the common drug interactions of Targiniq and Omeprazole, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Electrocardiogram qt prolonged
Intentional self-injury
Dyspnoea (difficult or laboured respiration)
Abdominal pain upper
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
C-reactive protein increased
Contusion (a type of hematoma of tissue in which capillaries)
Erythema (redness of the skin)

male:

Femur fracture
Pyrexia (fever)
Dizziness
Temporomandibular joint syndrome (pain at the temporomandibular joint due to various causes of increased muscle tension and spasm. it is believed that syndrome is a physical manifestation of psychological stress)
Vision blurred
Blood pressure increased
Glaucoma (increased fluid pressure in the eye with vision loss)
Hemiparesis (weakness on one side of the body)
Iritis (painful inflammation of the iris of the eye)
Necrotising panniculitis (inflammation of subcutaneous adipose tissue life threatening)

What are the common drug interactions of Targiniq and Omeprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthralgia (joint pain)
C-reactive protein increased
Contusion (a type of hematoma of tissue in which capillaries)
Erythema (redness of the skin)
Heart rate increased
Joint stiffness
Lymphadenopathy (disease or enlargement of lymph nodes)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)
Nasopharyngitis (inflammation of the nasopharynx)

30-39:

Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Blood phosphorus decreased
Fatigue (feeling of tiredness)
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Pruritus (severe itching of the skin)

40-49:

Femur fracture
Pyrexia (fever)
Device related infection
Febrile neutropenia (fever with reduced white blood cells)
Electrocardiogram qt prolonged
Hypotension (abnormally low blood pressure)
Intentional self-injury
Peripheral embolism (sudden interruption of blood flow to an organ or body part)

50-59:

Abdominal pain upper
Electrocardiogram qt prolonged
Hypotension (abnormally low blood pressure)
Intentional self-injury
Cerebral haemorrhage (bleeding within the brain)
Pulmonary embolism (blockage of the main artery of the lung)

60+:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Hypotension (abnormally low blood pressure)
Flushing (the warm, red condition of human skin)
Hyperhidrosis (abnormally increased sweating)
Hypersensitivity
Alopecia (absence of hair from areas of the body)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Blood pressure increased
Bradycardia (abnormally slow heart action)
Cerebral haemorrhage (bleeding within the brain)

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 10 people, 21.74%
Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 9 people, 19.57%
Burkitt Lymphoma (cancer of the lymphatic system): 9 people, 19.57%
Fever: 4 people, 8.70%
Femur Fracture: 4 people, 8.70%
Pain: 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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