Tasigna and Topamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tasigna (nilotinib hydrochloride monohydrate) and Topamax (topiramate). Common drug interactions include insomnia among females and convulsion among males.

The phase IV clinical study analyzes what interactions people have when they take Tasigna and Topamax. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Tasigna?

Tasigna has active ingredients of nilotinib hydrochloride monohydrate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 31,535 Tasigna users. Check the latest studies of Tasigna.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

On Jul, 11, 2026

27 people who take Tasigna and Topamax together, and have interactions are studied.

What are the common drug interactions of Tasigna and Topamax, by gender? *:

female:

Insomnia (sleeplessness)
Pruritus (severe itching of the skin)
Pain
Acne (skin problems that cause pimples)
Anaemia (lack of blood)
Arthralgia (joint pain)
Blood iron decreased
Bone pain
Breast cyst
Breast enlargement

male:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Abdominal pain
Neuropathy peripheral (surface nerve damage)
Oedema peripheral (superficial swelling)
Pancreatitis (inflammation of pancreas)
Pyrexia (fever)
Sleep disorder
Venous angioma of brain (benign tumour in the brain)
Blood pressure increased
Bone pain

What are the common drug interactions of Tasigna and Topamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anaemia (lack of blood)
Blood iron decreased
Bone pain
Breast cyst
Breast enlargement
Breast pain
Dry throat
Dysmenorrhoea (painful menstruation)
Ear disorder
Ear pain

40-49:

Pyrexia (fever)

50-59:

Back pain
Diarrhoea
Pancreatitis (inflammation of pancreas)

60+:

Cardiomegaly (increased size of heart than normal)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Dementia (madness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 15 people, 55.56%
Leukaemia (blood or bone marrow cancer): 2 people, 7.41%
Immunodeficiency Common Variable: 2 people, 7.41%
Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 2 people, 7.41%
Hypersensitivity: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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