Tazorac and Estradiol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tazorac (tazarotene) and Estradiol (estradiol). Common drug interactions include somnolence among females.

The phase IV clinical study analyzes what interactions people have when they take Tazorac and Estradiol. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Tazorac?

Tazorac has active ingredients of tazarotene. It is often used in acne. eHealthMe is studying from 1,046 Tazorac users. Check the latest studies of Tazorac.

What is Estradiol?

Estradiol has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 18,986 Estradiol users. Check the latest studies of Estradiol.

On Jul, 24, 2026

12 people who take Tazorac and Estradiol together, and have interactions are studied.

Tazorac and Estradiol drug interactions.

What are the common drug interactions of Tazorac and Estradiol, by gender? *:

female:

Somnolence (a state of near-sleep, a strong desire for sleep)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Neck pain
Nerve injury
Burning sensation
Erythema (redness of the skin)
Eye pruritus (eye itching)
Eye swelling
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Fatigue (feeling of tiredness)

male:

n/a

What are the common drug interactions of Tazorac and Estradiol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Eye pruritus (eye itching)
Eye swelling
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Pruritus (severe itching of the skin)
Rash
Swelling face
Burning sensation
Erythema (redness of the skin)
Eye pain

50-59:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Fatigue (feeling of tiredness)
Injection site pain
Retching (strong involuntary effort to vomit)
Vomiting projectile

60+:

Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 25.00%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 16.67%
Type 2 Diabetes: 1 person, 8.33%
Stress And Anxiety: 1 person, 8.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 8.33%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 8.33%
Neurotrophic Keratopathy (decreased corneal sensitivity and poor corneal healing): 1 person, 8.33%
Insomnia (sleeplessness): 1 person, 8.33%
Drowsiness: 1 person, 8.33%
Depression: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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