Tegretol and Dantrium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tegretol (carbamazepine) and Dantrium (dantrolene sodium). Common drug interactions include dehydration among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Tegretol and Dantrium. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Tegretol?

Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.

What is Dantrium?

Dantrium has active ingredients of dantrolene sodium. eHealthMe is studying from 1,408 Dantrium users. Check the latest studies of Dantrium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

67 people who take Tegretol and Dantrium together, and have interactions are studied.

Tegretol and Dantrium drug interactions.

What are the common drug interactions of Tegretol and Dantrium, by gender? *:

female:

Dehydration (dryness resulting from the removal of water)
Malaise (a feeling of general discomfort or uneasiness)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Oral discomfort (pain or irritation in mouth)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting
Abdominal pain
Acidosis (build-up of carbon dioxide in the blood)
Acute hepatic failure
Alkalosis

male:

Pneumonia
Pyrexia (fever)
Heart rate decreased
Heart rate irregular
Hydrocephalus (water on the brain)
Increased upper airway secretion
Oliguria (not enough urine)
Pulmonary oedema (fluid accumulation in the lungs)
Rhinorrhoea (watery mucus discharge from the nose)
Disease progression

What are the common drug interactions of Tegretol and Dantrium, by age (0-1 to 60+)? *:

0-1:

Injection site swelling
Respiratory failure (inadequate gas exchange by the respiratory system)
Pyrexia (fever)
Arrhythmia (irregular heartbeat)
Gastroenteritis adenovirus (inflammation of stomach and intestine by adeno virus infection)
Hyperkalaemia (damage to or disease of the kidney)
Pneumonia
Renal impairment (severely reduced kidney function)

2-9:

Fracture
Liver disorder (liver diseases)

10-19:

Bradycardia (abnormally slow heart action)
Atrioventricular block complete (heart block complete)
Atrioventricular block second degree (heart block second degree)
Drug level increased
Heart rate decreased
Heart rate irregular
Hydrocephalus (water on the brain)
Oliguria (not enough urine)
Pneumonia
Pulmonary oedema (fluid accumulation in the lungs)

20-29:

Cough
Increased upper airway secretion
Interstitial lung disease
Pneumonia
Pyrexia (fever)
Rhinorrhoea (watery mucus discharge from the nose)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Respiratory failure (inadequate gas exchange by the respiratory system)
Vomiting
Abdominal distension

30-39:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Vaginal haemorrhage (vaginal bleeding)
Abdominal pain
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Bladder disorder
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Drug maladministration
Fatigue (feeling of tiredness)
Headache (pain in head)

40-49:

Pyrexia (fever)
Hypokalaemia (low potassium)
Urine ketone body present
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Fatigue (feeling of tiredness)
Malaise (a feeling of general discomfort or uneasiness)
Phlebitis (inflammation of the walls of a vein)
Activated partial thromboplastin time shortened

50-59:

Gamma-glutamyltransferase increased
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Blood alkaline phosphatase increased
Crying
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression
Disuse syndrome (deterioration of body systems as a result of prescribed or unavoidable inactivity)
Drug resistance (reduction in effectiveness of a drug)
Dysphemia (stammering or stuttering)

60+:

Hypotension (abnormally low blood pressure)
Altered state of consciousness (altered state of mind)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Interstitial lung disease
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Lymphocyte count decreased
Malaise (a feeling of general discomfort or uneasiness)
Miosis (constriction of the pupil of the eye, resulting from a normal response to an increase in light)

What are the existing conditions these people have? *

Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 12 people, 17.91%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 8.96%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 7.46%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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