Zoloft and Communication disorder - a phase IV clinical study of FDA data

Summary:

Communication disorder is reported as a side effect among people who take Zoloft (sertraline hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Neurontin, and have Migraine.

The phase IV clinical study analyzes which people have Communication disorder when taking Zoloft. It is created by eHealthMe based on reports of 128,159 people who have side effects when taking Zoloft from the FDA, and is updated regularly.

What is Zoloft?

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,801 Zoloft users. Check the latest studies of Zoloft.

What is Communication disorder?

Communication disorder (speech and language disorder) is found to be associated with 484 drugs and 602 conditions by eHealthMe. Check the latest studies of Communication disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

128,159 people reported to have side effects when taking Zoloft.
Among them, 53 people (0.04%) have Communication disorder.

Could Zoloft cause Communication disorder?

Among these 53 people:

How long have people been on Zoloft when they have Communication disorder? *

What is the gender of people who have Communication disorder when taking Zoloft? *

female: 58 %
male: 42 %

What is the age of people who have Communication disorder when taking Zoloft? *

What are other drugs people take besides Zoloft? *

What are other side effects people have besides Communication disorder? *

High Blood Pressure: 12 people, 22.64%
Pain: 12 people, 22.64%
Confusional State: 11 people, 20.75%
Memory Loss: 11 people, 20.75%
Drug Ineffective: 10 people, 18.87%
Headache (pain in head): 10 people, 18.87%
Fatigue (feeling of tiredness): 9 people, 16.98%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 8 people, 15.09%
Tremor (trembling or shaking movements in one or more parts of your body): 7 people, 13.21%
Insomnia (sleeplessness): 7 people, 13.21%

What are the existing conditions these people have? *

Migraine (headache): 8 people, 15.09%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 11.32%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 9.43%
Gait Disturbance: 4 people, 7.55%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 3.77%
Drowsiness: 2 people, 3.77%
Parkinson's Disease: 2 people, 3.77%
Type 2 Diabetes: 2 people, 3.77%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 3.77%
Psychotic Disorder: 1 person, 1.89%

* Approximation only. Some reports may have incomplete information.

Do you take Zoloft and have Communication disorder?

- Check whether Communication disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Zoloft:

Zoloft (138,801 reports)

Browse all side effects of Zoloft:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Communication disorder:

Communication disorder (484 drugs)

Browse all the conditions that are associated with Communication disorder:

Communication disorder (602 conditions)

Related publications that referenced our studies

Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on sertraline hydrochloride (the active ingredients of Zoloft) and Zoloft (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.