Tegretol and Prograf drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tegretol (carbamazepine) and Prograf (tacrolimus). Common drug interactions include tremor among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Tegretol and Prograf. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Tegretol?

Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

On Jul, 05, 2026

62 people who take Tegretol and Prograf together, and have interactions are studied.

What are the common drug interactions of Tegretol and Prograf, by gender? *:

female:

Tremor (trembling or shaking movements in one or more parts of your body)
General physical health deterioration (weak health status)
Sinus node dysfunction (a group of abnormal heart rhythms)
Vomiting
Gestational hypertension (elevated blood pressure during pregnancy)
Premature labour
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Cardiorenal syndrome (kidney failure and heart failure)
Balance disorder
Alanine aminotransferase increased

male:

Pyrexia (fever)
Dyspnoea (difficult or laboured respiration)
Cardiomegaly (increased size of heart than normal)
Coma (state of unconsciousness lasting more than six hours)
Cough
Diarrhoea
Diplegia (paralysis of corresponding parts on both sides of the body)
Dizziness
Encephalitis viral (inflammation of the brain due to viral infection)
Fatigue (feeling of tiredness)

What are the common drug interactions of Tegretol and Prograf, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Cholangitis (infection of the bile duct)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cytolytic hepatitis (dissolution or destruction of a liver cell)
Gamma-glutamyltransferase increased
Hepatic enzyme increased
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

10-19:

n/a

20-29:

Gestational hypertension (elevated blood pressure during pregnancy)
Premature labour
Altered state of consciousness (altered state of mind)
Bradycardia (abnormally slow heart action)
Encephalitis viral (inflammation of the brain due to viral infection)
Albumin globulin ratio increased
Anxiety
Blood cholesterol increased
Blood creatine phosphokinase decreased
Blood glucose increased

30-39:

Cystitis bacterial (inflammation of the wall of the bladder by bacteria escherichia coli)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic nephropathy (diabetic kidney disease)
Gangrene (body tissue dies)
Hallucination (an experience involving the perception of something not present)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Wound infection staphylococcal

40-49:

Renal impairment (severely reduced kidney function)
Sudden death
Accidental exposure
Anticonvulsant toxicity
Arrhythmia (irregular heartbeat)
Ataxia (loss of full control of bodily movements)
Blood creatinine increased
Blood immunoglobulin g increased
Bradycardia (abnormally slow heart action)
Cardiac pacemaker replacement

50-59:

Cough
Diplegia (paralysis of corresponding parts on both sides of the body)
Multi-organ failure (multisystem organ failure)
Respiratory tract infection
West nile viral infection
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ataxia (loss of full control of bodily movements)
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
Decreased vibratory sense
Disseminated tuberculosis

60+:

Abdominal pain
General physical health deterioration (weak health status)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiomegaly (increased size of heart than normal)
Coma (state of unconsciousness lasting more than six hours)
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dyspnoea (difficult or laboured respiration)
Dysstasia (difficulty in standing)

What are the existing conditions these people have? *

Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 14 people, 22.58%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

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