Tegretol and Restasis drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Tegretol (carbamazepine) and Restasis (cyclosporine). Common drug interactions include blister among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Tegretol and Restasis. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.
What is Tegretol?
Tegretol has active ingredients of carbamazepine. It is often used in epilepsy. eHealthMe is studying from 45,969 Tegretol users. Check the latest studies of Tegretol.
What is Restasis?
Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.
61 people who take Tegretol and Restasis together, and have interactions are studied.

What are the common drug interactions of Tegretol and Restasis, by gender? *:
female:
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Sinusitis (inflammation of sinus)
- Cystitis (inflammation of the wall of the bladder)
- Dysarthria (speech disorder)
- Ear infection
- Gait disturbance
- Muscular weakness (muscle weakness)
- Urinary tract infection
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Ataxia (loss of full control of bodily movements)
male:
- Back pain
- Eye irritation
- Mitral valve incompetence (inefficient heart valve)
- Mobility decreased (ability to move is reduced)
- Pain
- Tricuspid valve incompetence (inefficient heart valve)
- Urinary tract infection
- Vision blurred
- Vomiting
- Eye pain
What are the common drug interactions of Tegretol and Restasis, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Cholecystitis chronic (long lasting infection of gallbladder)
- Injury
- Pain
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Appendix disorder
30-39:
n/a
40-49:
- Haemolytic anaemia (anaemia due to haemolysis)
- Malignant neoplasm of islets of langerhans (cancer tumour of pancreas)
- Thyroid cancer
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Visual acuity reduced (reduced clearness of vision)
50-59:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Ataxia (loss of full control of bodily movements)
- Balance disorder
- Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
- Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
- Dysarthria (speech disorder)
- Gait disturbance
- Muscular weakness (muscle weakness)
- Neuropathy peripheral (surface nerve damage)
- Spasmodic dysphonia (a voice disorder characterized by involuntary movements or spasms of one or more muscles of the larynx)
60+:
- Cystitis (inflammation of the wall of the bladder)
- Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
- Sinusitis (inflammation of sinus)
- Urinary tract infection
- Eye irritation
- Tooth abscess (pus formation in tooth)
- Tooth fracture
- Upper respiratory tract infection
- Drug hypersensitivity
- Fatigue (feeling of tiredness)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 10 people, 16.39%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 13.11%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 9.84%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 9.84%
- Nausea (feeling of having an urge to vomit): 6 people, 9.84%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 9.84%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 9.84%
- Urinary Tract Infection: 5 people, 8.20%
- Stress And Anxiety: 5 people, 8.20%
- Pain: 5 people, 8.20%
* Approximation only. Some reports may have incomplete information.
Do you take Tegretol and Restasis?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Tegretol and Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Tegretol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tegretol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restasis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
- Puvanendran R, Teo HZ, "Case report of use of Black Cohosh for carbamazepine induced hot flushes in a post menopausal woman", Maturitas, 2017 Jun .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- Arshad F, Ladakhi Y, Khan MA, "A rare case of carbamazepine induced pancreatitis", International Journal of Students’ Research, 2013 Jul .
- Yava?o?lu I, Sarg?n G, Demirbulat A, "Carbamazepine and hematological malignancies", Turkish journal of haematology: official journal of Turkish Society of Haematology, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on carbamazepine and cyclosporine (the active ingredients of Tegretol and Restasis, respectively), and Tegretol and Restasis (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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