Tekturna and Premarin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tekturna (aliskiren hemifumarate) and Premarin (estrogens, conjugated). Common drug interactions include diarrhoea among females and chest discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Tekturna and Premarin. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

What is Premarin?

Premarin has active ingredients of estrogens, conjugated. It is often used in hormone replacement therapy. eHealthMe is studying from 99,630 Premarin users. Check the latest studies of Premarin.

On Jul, 23, 2026

42 people who take Tekturna and Premarin together, and have interactions are studied.

Tekturna and Premarin drug interactions.

What are the common drug interactions of Tekturna and Premarin, by gender? *:

female:

Diarrhoea
Drug effect decreased
Drug ineffective
Glossodynia (a burning or painful sensation in the tongue)
Nephrogenic anaemia (anaemia due to kidney disease)
Oedema (fluid collection in tissue)
Pain
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Pyrexia (fever)
Renal failure (kidney dysfunction)

male:

Chest discomfort
Flushing (the warm, red condition of human skin)

What are the common drug interactions of Tekturna and Premarin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Injection site pruritus (severe itching at injection site)
Injection site rash

50-59:

Nephrogenic anaemia (anaemia due to kidney disease)
Oedema (fluid collection in tissue)
Pain
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Renal failure (kidney dysfunction)
Renal impairment (severely reduced kidney function)
Swollen tongue (swelling of tongue)
Tongue oedema (swelling of tongue)
Drug ineffective
Addison's disease (addison's disease, a hormonal disorder disease)

60+:

Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)
Diarrhoea
Dysarthria (speech disorder)
Dysphagia (a condition in which swallowing is difficult or painful)
Lip oedema (swelling of lip)
Malaise (a feeling of general discomfort or uneasiness)
Muscle spasms (muscle contraction)
Nephrogenic anaemia (anaemia due to kidney disease)
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 16.67%
Sleep Disorder: 5 people, 11.90%
High Blood Cholesterol: 5 people, 11.90%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 9.52%
Osteoporosis (bones weak and more likely to break): 4 people, 9.52%
Insomnia (sleeplessness): 4 people, 9.52%
Pain: 3 people, 7.14%
Gastrointestinal Motility Disorder (abnormal intestinal contractions): 3 people, 7.14%
Diabetes: 3 people, 7.14%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Tekturna and Premarin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously