Tekturna and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tekturna (aliskiren hemifumarate) and Seroquel (quetiapine fumarate). Common drug interactions include migraine among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Tekturna and Seroquel. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Tekturna?

Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

27 people who take Tekturna and Seroquel together, and have interactions are studied.

Tekturna and Seroquel drug interactions.

What are the common drug interactions of Tekturna and Seroquel, by gender? *:

female:

Migraine (headache)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Necrobiosis lipoidica diabeticorum (a necrotizing skin condition that usually occurs in patients with diabetes)
Nephrogenic anaemia (anaemia due to kidney disease)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Peptic ulcer
Seronegative arthritis (a joint disease negative for rheumatoid arthritis)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Thoracic haemorrhage (bleeding from chest cavity)
Pneumonia

male:

Renal failure (kidney dysfunction)
Abdominal pain
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Urinary tract infection
Vision blurred
Aggression
Agitation (state of anxiety or nervous excitement)
Confusional state

What are the common drug interactions of Tekturna and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Bradycardia (abnormally slow heart action)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Dyspepsia (indigestion)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hyperglycaemia (high blood sugar)
Hyperlipidaemia (presence of excess lipids in the blood)
Leukocytosis (increased white blood cells)
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)

30-39:

Chronic kidney disease
Hypoglycaemia (deficiency of glucose in the bloodstream)
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Type 1 diabetes mellitus

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Chest injury
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Gallbladder disorder
Mass
Neoplasm (tumour)
Pneumonia

50-59:

Chronic kidney disease
Flushing (the warm, red condition of human skin)
Nephrogenic anaemia (anaemia due to kidney disease)
Post-traumatic stress disorder
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Secondary hyperthyroidism

60+:

Weight decreased
Pneumonia
Incision site erythema (redness of the skin at incision site)
Injection site bruising
Injection site pain
Oedema peripheral (superficial swelling)
Parkinson's disease
Pruritus (severe itching of the skin)
Rash
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 37.04%
Asthma: 9 people, 33.33%
Stress And Anxiety: 8 people, 29.63%
Pain: 8 people, 29.63%
High Blood Cholesterol: 7 people, 25.93%
Panic Disorder: 7 people, 25.93%
Depression: 6 people, 22.22%
Gastric Disorder (disease of stomach): 4 people, 14.81%
Insomnia (sleeplessness): 4 people, 14.81%
Blood Pressure Abnormal: 4 people, 14.81%

* Approximation only. Some reports may have incomplete information.

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