Temodar and Ms contin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Temodar (temozolomide) and Ms contin (morphine sulfate). Common drug interactions include injury among females and haematocrit decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Temodar and Ms contin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Temodar?

Temodar has active ingredients of temozolomide. It is often used in glioblastoma multiforme. eHealthMe is studying from 6,683 Temodar users. Check the latest studies of Temodar.

What is Ms contin?

Ms contin has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 69,289 Ms contin users. Check the latest studies of Ms contin.



On Jul, 18, 2026

19 people who take Temodar and Ms contin together, and have interactions are studied.

Temodar and Ms contin drug interactions.

What are the common drug interactions of Temodar and Ms Contin, by gender? *:

female:

  1. Injury
  2. Insomnia (sleeplessness)
  3. Intervertebral disc degeneration (spinal disc degeneration)
  4. Kidney small
  5. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  6. Multiple fractures
  7. Neuropathic ulcer (nerve damage in foot leads to sensation loss and person puts lots of pressure and gets ulcer)
  8. Oedema peripheral (superficial swelling)
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Osteolysis (dissolution of bone)

male:

  1. Haematocrit decreased
  2. Blood potassium decreased
  3. Arteriosclerosis (thickening and hardening of arteries)
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Atelectasis (partial or complete collapse of the lung)
  6. Bladder hypertrophy (bladder overgrowth- increase in cell size)
  7. Bladder obstruction
  8. Blood albumin decreased
  9. Blood alkaline phosphatase increased
  10. Blood chloride increased

What are the common drug interactions of Temodar and Ms Contin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Chest pain
  2. Pulmonary embolism (blockage of the main artery of the lung)

20-29:

n/a

30-39:

n/a

40-49:

  1. Disease progression
  2. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  3. Fall
  4. Haematocrit decreased
  5. Thrombocytopenia (decrease of platelets in blood)
  6. White blood cell count increased
  7. Blood alkaline phosphatase increased
  8. Blood lactate dehydrogenase increased

50-59:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
  3. Asthenia (weakness)
  4. Disease progression
  5. Leukopenia (less number of white blood cells in blood)
  6. Overdose
  7. Pyrexia (fever)
  8. Thrombocytopenia (decrease of platelets in blood)
  9. Uterine leiomyosarcoma (uterus cancer of smooth muscle connective tissue)

60+:

  1. Blood lactate dehydrogenase increased
  2. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  3. Bone fissure
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Bruxism (habitual grinding of the teeth, typically during sleep)
  6. Cellulitis (infection under the skin)
  7. Cerebral infarction (less blood supply to brain resulting tissue damage)
  8. Confusional state
  9. Culture urine positive
  10. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)

What are the existing conditions these people have? *

  1. High Blood Pressure: 2 people, 10.53%
  2. Uterine Leiomyosarcoma (uterus cancer of smooth muscle connective tissue): 1 person, 5.26%
  3. Pulmonary Tuberculosis (lungs tuberculosis): 1 person, 5.26%
  4. Pulmonary Embolism (blockage of the main artery of the lung): 1 person, 5.26%
  5. Neuroendocrine Tumor: 1 person, 5.26%
  6. Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 1 person, 5.26%
  7. Histiocytosis Haematophagic: 1 person, 5.26%
  8. Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 1 person, 5.26%
  9. Ewing's Sarcoma (malignant small, round, blue cell tumour): 1 person, 5.26%
  10. Breakthrough Pain: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Temodar and Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Temodar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ms contin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Temodar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ms contin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on temozolomide and morphine sulfate (the active ingredients of Temodar and Ms contin, respectively), and Temodar and Ms contin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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