Temovate and Prinzide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Temovate (clobetasol propionate) and Prinzide (hydrochlorothiazide; lisinopril). Common drug interactions include chronic kidney disease among females and antinuclear antibody increased among males.
The phase IV clinical study analyzes what interactions people have when they take Temovate and Prinzide. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Temovate?
Temovate has active ingredients of clobetasol propionate. eHealthMe is studying from 1,392 Temovate users. Check the latest studies of Temovate.
What is Prinzide?
Prinzide has active ingredients of hydrochlorothiazide; lisinopril. It is often used in high blood pressure. eHealthMe is studying from 2,218 Prinzide users. Check the latest studies of Prinzide.
11 people who take Temovate and Prinzide together, and have interactions are studied.

What are the common drug interactions of Temovate and Prinzide, by gender? *:
female:
- Chronic kidney disease
- Renal injury (kidney injury)
- Depression
- Pruritus (severe itching of the skin)
- Rash
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Rash macular (small, flat red spots)
- Therapeutic response decreased (less preventive response)
- Abdominal discomfort
- Alopecia (absence of hair from areas of the body)
male:
- Antinuclear antibody increased
- Arthralgia (joint pain)
- Myalgia (muscle pain)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pain
- Pain in extremity
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Discomfort
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
What are the common drug interactions of Temovate and Prinzide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Chronic kidney disease
- Renal injury (kidney injury)
- Depression
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
60+:
- Pruritus (severe itching of the skin)
- Rash
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Diarrhoea
- Discomfort
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Headache (pain in head)
- Hypersensitivity
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 27.27%
- Pain: 3 people, 27.27%
- High Blood Cholesterol: 3 people, 27.27%
- Kidney Infection (Pyelonephritis): 3 people, 27.27%
- Infection: 3 people, 27.27%
- Wheezing (a high-pitched whistling sound made while you breath): 2 people, 18.18%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 18.18%
- Indigestion: 1 person, 9.09%
- Cough: 1 person, 9.09%
- Headache (pain in head): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Temovate and Prinzide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Temovate and Prinzide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Temovate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Prinzide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Temovate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prinzide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on clobetasol propionate and hydrochlorothiazide; lisinopril (the active ingredients of Temovate and Prinzide, respectively), and Temovate and Prinzide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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