Methylprednisolone and Amiodarone hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylprednisolone (methylprednisolone) and Amiodarone hydrochloride (amiodarone hydrochloride). Common drug interactions include infusion related reaction among females and toxic epidermal necrolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Methylprednisolone and Amiodarone hydrochloride. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Methylprednisolone?

Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.

What is Amiodarone hydrochloride?

Amiodarone hydrochloride has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 10,061 Amiodarone hydrochloride users. Check the latest studies of Amiodarone hydrochloride.

On Jul, 10, 2026

73 people who take Methylprednisolone and Amiodarone hydrochloride together, and have interactions are studied.

Methylprednisolone and Amiodarone hydrochloride drug interactions.

What are the common drug interactions of Methylprednisolone and Amiodarone Hydrochloride, by gender? *:

female:

Infusion related reaction
Joint swelling
Nasopharyngitis (inflammation of the nasopharynx)
Arthralgia (joint pain)
Pain
Asthenia (weakness)
Gait disturbance
Herpes zoster
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pneumonia

male:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Enterobacter pneumonia (lung inflammation caused by bacteria of the family enterobacteriaceae)
Electrocardiogram qt prolonged
Enterobacter test positive
Haemodynamic instability (disturbances in the blood movement in our body)
Hypoxia (low oxygen in tissues)
Interstitial lung disease
Multi-organ failure (multisystem organ failure)
Obliterative bronchiolitis (bronchiolar inflammation)
Post procedural complication

What are the common drug interactions of Methylprednisolone and Amiodarone Hydrochloride, by age (0-1 to 60+)? *:

0-1:

Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Enterobacter pneumonia (lung inflammation caused by bacteria of the family enterobacteriaceae)
Escherichia infection (bacterial infection by escherichia coli)
Staphylococcal infection (an infection with staphylococcus bacteria)

2-9:

n/a

10-19:

n/a

20-29:

Asthenia (weakness)
Brain death
Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
Cardiac failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dysuria (painful or difficult urination)
General physical health deterioration (weak health status)
Hypotension (abnormally low blood pressure)
Lethargy (tiredness)
Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

Hypokinesia (decreased bodily movement)
Left ventricular dysfunction

50-59:

Gait disturbance
Gastric disorder (disease of stomach)
Glycosylated haemoglobin increased
Heart rate increased
Hepatic enzyme increased
Infection
Infusion related reaction
Insomnia (sleeplessness)
Joint stiffness
Joint swelling

60+:

Hypoxia (low oxygen in tissues)
Alveolitis (inflammation in the socket of a tooth)
Enterococcal infection
Nausea (feeling of having an urge to vomit)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Vomiting
Respiratory failure (inadequate gas exchange by the respiratory system)
Blood bilirubin increased
Blood pressure increased
Drug ineffective

What are the existing conditions these people have? *

Breast Cancer: 23 people, 31.51%
High Blood Pressure: 15 people, 20.55%
Constipation: 12 people, 16.44%
Fever: 12 people, 16.44%
Pneumonia: 12 people, 16.44%
Breast Cancer Female: 11 people, 15.07%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 10 people, 13.70%
Gait Disturbance: 9 people, 12.33%
Tracheobronchitis (an inflammation or infection, which affects the trachea and bronchi of respiratory tract): 9 people, 12.33%
Depression: 9 people, 12.33%

* Approximation only. Some reports may have incomplete information.

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