Temsirolimus and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Temsirolimus (temsirolimus) and Profen (ibuprofen). Common drug interactions include cardiac arrest among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Temsirolimus and Profen. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Temsirolimus?

Temsirolimus has active ingredients of temsirolimus. eHealthMe is studying from 3,573 Temsirolimus users. Check the latest studies of Temsirolimus.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 12, 2026

43 people who take Temsirolimus and Profen together, and have interactions are studied.

Temsirolimus and Profen drug interactions.

What are the common drug interactions of Temsirolimus and Profen, by gender? *:

female:

Cardiac arrest
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Respiratory failure (inadequate gas exchange by the respiratory system)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Vomiting
Hypertension (high blood pressure)
Anaemia (lack of blood)
Diarrhoea

male:

Nausea (feeling of having an urge to vomit)
Anaemia (lack of blood)
Adrenal gland cancer metastatic (adrenal gland cancer-spread of cancer to other parts of the body)
Anger
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Blood testosterone decreased
Bone disorder
Bone marrow failure
Cardiac failure congestive

What are the common drug interactions of Temsirolimus and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypotension (abnormally low blood pressure)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Sepsis (a severe blood infection that can lead to organ failure and death)
Stomatitis (inflammation of mucous membrane of mouth)
Acidosis (build-up of carbon dioxide in the blood)
Cardiac arrest
Encephalopathy (functioning of the brain is affected by some agent or condition)

20-29:

n/a

30-39:

Disease progression
Hypertension (high blood pressure)

40-49:

Immunosuppression
Injury
Inspiratory capacity decreased
Loose tooth
Loss of proprioception (loss of senses of body and parts)
Lung disorder (lung disease)
Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
Malignant neoplasm progression (cancer tumour came back)
Mass
Mastication disorder (disease of chewing food)

50-59:

Vomiting
Dizziness
Nausea (feeling of having an urge to vomit)
Hypertension (high blood pressure)
Abdominal pain upper
Back disorder
Cardiac disorder
Cardiac failure congestive
Cough
Drug ineffective

60+:

Anaemia (lack of blood)
Cerebral haemorrhage (bleeding within the brain)
Cardiac arrest
Cardiac failure acute
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal discomfort
Cough
Decreased appetite
Epistaxis (bleed from the nose)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 12 people, 27.91%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 10 people, 23.26%
Bone Density Decreased: 10 people, 23.26%
B Precursor Type Acute Leukaemia (lymphoid cancer): 9 people, 20.93%
Klebsiella Infection: 6 people, 13.95%
Renal Cell Carcinoma (a kidney cancer): 5 people, 11.63%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 5 people, 11.63%

* Approximation only. Some reports may have incomplete information.

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