Tequin and Keppra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tequin (gatifloxacin) and Keppra (levetiracetam). Common drug interactions include bone marrow depression among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Tequin and Keppra. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Tequin?

Tequin has active ingredients of gatifloxacin. eHealthMe is studying from 4,645 Tequin users. Check the latest studies of Tequin.

What is Keppra?

Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 73,504 Keppra users. Check the latest studies of Keppra.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

14 people who take Tequin and Keppra together, and have interactions are studied.

What are the common drug interactions of Tequin and Keppra, by gender? *:

female:

Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
Nausea (feeling of having an urge to vomit)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Vomiting
Syncope (loss of consciousness with an inability to maintain postural tone)
Syncope vasovagal (malfunction in the parts of the nervous system leads to consciousness with an inability to maintain postural tone)
Abdominal pain
Anxiety
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Erythema (redness of the skin)
Skin induration (an abnormally hard spot or area on the skin)
Skin tightness
Arthralgia (joint pain)
Deformity (disfigurement)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
General physical health deterioration (weak health status)
Hyperkeratosis (thickening of the outer layer of the skin)
Hypoaesthesia (reduced sense of touch or sensation)

What are the common drug interactions of Tequin and Keppra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)

50-59:

Arthralgia (joint pain)
Deformity (disfigurement)
Erythema (redness of the skin)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Gait disturbance
General physical health deterioration (weak health status)
Hyperkeratosis (thickening of the outer layer of the skin)
Hypoaesthesia (reduced sense of touch or sensation)
Joint contracture (a permanent shortening of a muscle or joint)
Joint range of motion decreased (disease of joint movement)

60+:

Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
Nausea (feeling of having an urge to vomit)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Coma (state of unconsciousness lasting more than six hours)
Confusional state
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Diarrhoea
Haematocrit
Haemorrhage intracranial (bleeding within the skull)
International normalised ratio decreased

What are the existing conditions these people have? *

Nuclear Magnetic Resonance Imaging Brain: 5 people, 35.71%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 28.57%
Tumor: 2 people, 14.29%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 2 people, 14.29%
Stress And Anxiety: 2 people, 14.29%
Pain: 2 people, 14.29%
Neoplasm Malignant (cancer tumour): 2 people, 14.29%
Constipation: 2 people, 14.29%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 1 person, 7.14%
Metastases To Central Nervous System (cancer spreads to central nervous system): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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