Tessalon and Feldene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tessalon (benzonatate) and Feldene (piroxicam). Common drug interactions include anaemia among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Tessalon and Feldene. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Tessalon?

Tessalon has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 6,493 Tessalon users. Check the latest studies of Tessalon.

What is Feldene?

Feldene has active ingredients of piroxicam. It is often used in arthritis. eHealthMe is studying from 3,913 Feldene users. Check the latest studies of Feldene.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

15 people who take Tessalon and Feldene together, and have interactions are studied.

What are the common drug interactions of Tessalon and Feldene, by gender? *:

female:

Anaemia (lack of blood)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Anxiety
Blood chloride decreased
Blood glucose increased
Depression
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Interstitial lung disease
Mitral valve incompetence (inefficient heart valve)

male:

Blood pressure increased
Chest pain
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Dyspnoea (difficult or laboured respiration)
Constipation
Gastrointestinal tract adenoma (a benign tumour (-oma) of glandular origin in digestive tract)
Haematocrit decreased
Haemoglobin decreased
Heart rate increased
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract)

What are the common drug interactions of Tessalon and Feldene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac disorder
Migraine (headache)
Type 1 diabetes mellitus
Cardiac failure congestive
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Joint injury
Thrombosis (formation of a blood clot inside a blood vessel)
Viral cardiomyopathy (weakness in the muscle of the heart due to viral infection)

30-39:

n/a

40-49:

n/a

50-59:

Blood pressure increased
Chest pain
Dyspnoea (difficult or laboured respiration)
Haematocrit decreased
Haemoglobin decreased
Heart rate increased
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

60+:

Anaemia (lack of blood)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Platelet count increased
Pleural effusion (water on the lungs)
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sinusitis (inflammation of sinus)
Tricuspid valve incompetence (inefficient heart valve)
Asthenia (weakness)

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 4 people, 26.67%
Insomnia (sleeplessness): 3 people, 20.00%
Stress And Anxiety: 3 people, 20.00%
Multiple Myeloma (cancer of the plasma cells): 2 people, 13.33%
Constipation: 2 people, 13.33%
Enlarged Prostate: 2 people, 13.33%
Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 13.33%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 13.33%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 13.33%
Tumor Pain: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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