Serenoa repens and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Serenoa repens (saw palmetto) and Flonase (fluticasone propionate). Common drug interactions include bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Serenoa repens and Flonase. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Serenoa repens?

Serenoa repens has active ingredients of saw palmetto. eHealthMe is studying from 628 Serenoa repens users. Check the latest studies of Serenoa repens.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

12 people who take Serenoa repens and Flonase together, and have interactions are studied.

Serenoa repens and Flonase drug interactions.

What are the common drug interactions of Serenoa Repens and Flonase, by gender? *:

female:

n/a

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dyspnoea (difficult or laboured respiration)
Cystic fibrosis (disease of the secretary glands)
Cytomegalovirus infection
Decreased activity
Depression
Dizziness
Drug ineffective
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Joint swelling

What are the common drug interactions of Serenoa Repens and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Hepatic enzyme increased
Muscle spasms (muscle contraction)
Red blood cell count decreased

50-59:

n/a

60+:

Dyspnoea (difficult or laboured respiration)
Alopecia (absence of hair from areas of the body)
Joint swelling
Lung disorder (lung disease)
Oedema peripheral (superficial swelling)
Pneumonia
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Vision blurred
Weight increased
Wheezing (a high-pitched whistling sound made while you breath)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 3 people, 25.00%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 1 person, 8.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 8.33%
Multiple Myeloma (cancer of the plasma cells): 1 person, 8.33%
Depression: 1 person, 8.33%
Asthma: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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