Testopel and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Testopel (testosterone) and Profen (ibuprofen). Common drug interactions include implant site induration among females and blood alkaline phosphatase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Testopel and Profen. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Testopel?

Testopel has active ingredients of testosterone. eHealthMe is studying from 1,881 Testopel users. Check the latest studies of Testopel.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 21, 2026

16 people who take Testopel and Profen together, and have interactions are studied.

What are the common drug interactions of Testopel and Profen, by gender? *:

female:

Implant site induration
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Anxiety
Blood pressure increased
Delusion (a false belief or opinion)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

male:

Blood alkaline phosphatase increased
Blood triglycerides increased
Arthralgia (joint pain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diastolic dysfunction
Fatigue (feeling of tiredness)
Lung disorder (lung disease)
Pulmonary embolism (blockage of the main artery of the lung)
Implant site erythema (redness at implant site)
Injury

What are the common drug interactions of Testopel and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Emotional distress
Implant site induration
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Implant site erythema (redness at implant site)
Injury
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Wound
Arthralgia (joint pain)
Bone density decreased
Bone loss

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diastolic dysfunction
Lung disorder (lung disease)
Pulmonary embolism (blockage of the main artery of the lung)
Anxiety
Blood pressure increased
Delusion (a false belief or opinion)

60+:

Blood alkaline phosphatase increased
Blood triglycerides increased
Affect lability (emotional incontinence)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Cardiac arrest
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the existing conditions these people have? *

Blood Testosterone Decreased: 4 people, 25.00%
Gout (uric acid crystals building up in the body): 3 people, 18.75%
Primary Myelofibrosis (primary disorder of the bone marrow): 3 people, 18.75%
Laxative Supportive Care: 3 people, 18.75%
Bronchial Disorder: 3 people, 18.75%
Cardiac Disorder: 3 people, 18.75%
Cardiac Failure Chronic: 3 people, 18.75%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 18.75%
Diabetes: 2 people, 12.50%
Back Pain: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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