Testosterone cypionate and Vitamin b12 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Testosterone cypionate (testosterone cypionate) and Vitamin b12 (cobalamin). Common drug interactions include bipolar disorder among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Testosterone cypionate and Vitamin b12. It is created by eHealthMe based on reports of 62 people who take the same drugs from the FDA, and is updated regularly.

What is Testosterone cypionate?

Testosterone cypionate has active ingredients of testosterone cypionate. It is often used in testosterone. eHealthMe is studying from 1,926 Testosterone cypionate users. Check the latest studies of Testosterone cypionate.

What is Vitamin b12?

Vitamin b12 has active ingredients of cobalamin. It is often used in vitamin b12 deficiency. eHealthMe is studying from 121,681 Vitamin b12 users. Check the latest studies of Vitamin b12.



On Aug, 02, 2026

62 people who take Testosterone cypionate and Vitamin b12 together, and have interactions are studied.

Testosterone cypionate and Vitamin b12 drug interactions.

What are the common drug interactions of Testosterone Cypionate and Vitamin B12, by gender? *:

female:

  1. Bipolar disorder (mood disorder)
  2. Nausea (feeling of having an urge to vomit)
  3. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  4. Depression
  5. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  6. Muscle spasms (muscle contraction)
  7. Vitamin d decreased
  8. Dystonia (abnormal muscle tone)
  9. Injection site urticaria (rash of round, red welts on the skin at injection site)
  10. Muscle contractions involuntary (uncontrolled muscle contraction)

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Dehydration (dryness resulting from the removal of water)
  3. Prostatic specific antigen increased
  4. Rash pruritic (redness with itching)
  5. Weight decreased
  6. Headache (pain in head)
  7. Pruritus (severe itching of the skin)
  8. Back pain
  9. Balance disorder
  10. Diarrhoea

What are the common drug interactions of Testosterone Cypionate and Vitamin B12, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Weight increased

20-29:

  1. Nausea (feeling of having an urge to vomit)
  2. Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
  3. Depression
  4. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  5. Muscle spasms (muscle contraction)
  6. Vitamin d decreased
  7. Dystonia (abnormal muscle tone)
  8. Fall
  9. Femur fracture
  10. Injection site urticaria (rash of round, red welts on the skin at injection site)

30-39:

  1. Muscle atrophy (a decrease in the mass of the muscle)
  2. Throat tightness
  3. Trismus (reduced opening of the jaws)

40-49:

  1. Abdominal pain
  2. Chest pain
  3. Dyspnoea (difficult or laboured respiration)
  4. Dysstasia (difficulty in standing)
  5. Headache (pain in head)
  6. Heart rate increased
  7. Infusion related reaction
  8. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  9. Nasal inflammation (inflammation of nose)
  10. Nausea (feeling of having an urge to vomit)

50-59:

  1. Influenza like illness
  2. Infusion related reaction
  3. Joint dislocation (a joint position is changed from normal position)
  4. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  5. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  6. Muscle rupture (tear in muscle)
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Nausea (feeling of having an urge to vomit)
  9. Post procedural complication
  10. Post procedural infection

60+:

  1. Dehydration (dryness resulting from the removal of water)
  2. Nausea (feeling of having an urge to vomit)
  3. Weight decreased
  4. Psoriasis (immune-mediated disease that affects the skin)
  5. Blood pressure increased
  6. Constipation
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Heart rate increased
  9. Infusion site pain
  10. Infusion site pruritus (severe itching at infusion site)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 17.74%
  2. Immunodeficiency Common Variable: 9 people, 14.52%
  3. Drowsiness: 8 people, 12.90%
  4. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 12.90%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 11.29%
  6. High Blood Pressure: 5 people, 8.06%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 8.06%
  8. Blood Testosterone Decreased: 5 people, 8.06%
  9. Pain: 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Testosterone cypionate and Vitamin b12?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Testosterone cypionate and Vitamin b12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Testosterone cypionate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vitamin b12:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Testosterone cypionate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin b12 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on testosterone cypionate and cobalamin (the active ingredients of Testosterone cypionate and Vitamin b12, respectively), and Testosterone cypionate and Vitamin b12 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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