Testosterone and Clonidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Testosterone (testosterone) and Clonidine (clonidine). Common drug interactions include lung infiltration among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Testosterone and Clonidine. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Testosterone?

Testosterone has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 6,457 Testosterone users. Check the latest studies of Testosterone.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.



On Aug, 10, 2026

55 people who take Testosterone and Clonidine together, and have interactions are studied.

Testosterone and Clonidine drug interactions.

What are the common drug interactions of Testosterone and Clonidine, by gender? *:

female:

  1. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  2. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  3. Myalgia (muscle pain)
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  5. Osteonecrosis of jaw (death of bone of jaw)
  6. Osteoporosis (bones weak and more likely to break)
  7. Osteosclerosis (an elevation in bone density)
  8. Pain
  9. Pleural effusion (water on the lungs)
  10. Pulmonary mass

male:

  1. Pain
  2. Renal failure (kidney dysfunction)
  3. Diarrhoea
  4. Fatigue (feeling of tiredness)
  5. Nausea (feeling of having an urge to vomit)
  6. Osteopenia (a condition where bone mineral density is lower than normal)
  7. Osteoporosis (bones weak and more likely to break)
  8. Anaemia (lack of blood)
  9. Balance disorder
  10. Cardiovascular disorder (heart diseases)

What are the common drug interactions of Testosterone and Clonidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Drug ineffective
  2. Anaemia (lack of blood)
  3. Cardiac failure
  4. Cardiovascular disorder (heart diseases)
  5. Lung neoplasm malignant (cancer tumour of lung)
  6. Pulmonary oedema (fluid accumulation in the lungs)
  7. Renal failure (kidney dysfunction)
  8. Thrombosis (formation of a blood clot inside a blood vessel)
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Bone density decreased

40-49:

  1. Pain
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Chronic kidney disease
  4. Renal failure (kidney dysfunction)
  5. Emotional distress
  6. Back pain
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Osteoporosis (bones weak and more likely to break)
  9. Bone density decreased
  10. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

  1. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
  2. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  3. Hypophagia (reduced food intake)
  4. Inappropriate antidiuretic hormone secretion
  5. Infection
  6. Inflammation
  7. Injury
  8. Intervertebral disc disorder (spinal disc disorder)
  9. Jaw disorder (jaw disease)
  10. Joint swelling

60+:

  1. Abdominal pain upper
  2. Arthralgia (joint pain)
  3. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  4. Dyspepsia (indigestion)
  5. Dyspnoea (difficult or laboured respiration)
  6. Femur fracture
  7. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  8. Heart rate increased
  9. Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
  10. Hyperhidrosis (abnormally increased sweating)

What are the existing conditions these people have? *

  1. Renal Cell Carcinoma (a kidney cancer): 8 people, 14.55%
  2. Stress And Anxiety: 7 people, 12.73%
  3. Pain: 7 people, 12.73%
  4. Hiv Infection: 7 people, 12.73%
  5. Depression: 5 people, 9.09%
  6. Quit Smoking: 3 people, 5.45%
  7. Osteoporosis (bones weak and more likely to break): 3 people, 5.45%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 5.45%
  9. Erection Problems: 3 people, 5.45%
  10. Chest Pain: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Testosterone and Clonidine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Testosterone and Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Testosterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Testosterone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on testosterone and clonidine (the active ingredients of Testosterone and Clonidine, respectively), and Testosterone and Clonidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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