Testosterone and Morphine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Testosterone (testosterone) and Morphine (morphine sulfate). Common drug interactions include therapeutic response decreased among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Testosterone and Morphine. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Testosterone?

Testosterone has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 6,457 Testosterone users. Check the latest studies of Testosterone.

What is Morphine?

Morphine has active ingredients of morphine sulfate. It is often used in pain. eHealthMe is studying from 182,913 Morphine users. Check the latest studies of Morphine.



On Jul, 13, 2026

95 people who take Testosterone and Morphine together, and have interactions are studied.

Testosterone and Morphine drug interactions.

What are the common drug interactions of Testosterone and Morphine, by gender? *:

female:

  1. Therapeutic response decreased (less preventive response)
  2. Death
  3. Anxiety
  4. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  5. Drug ineffective
  6. Dyspnoea (difficult or laboured respiration)
  7. Headache (pain in head)
  8. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  9. Infection
  10. Injury

male:

  1. Arthralgia (joint pain)
  2. Pneumonia
  3. Diarrhoea
  4. Hepatic enzyme increased
  5. Abdominal pain
  6. Fall
  7. Headache (pain in head)
  8. Neuropathy peripheral (surface nerve damage)
  9. Chest pain
  10. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

What are the common drug interactions of Testosterone and Morphine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Pyrexia (fever)
  2. Vomiting
  3. Abdominal pain
  4. Agitation (state of anxiety or nervous excitement)
  5. Blood growth hormone increased
  6. Brain injury
  7. Breath odour
  8. Chest pain
  9. Constipation
  10. Contusion (a type of hematoma of tissue in which capillaries)

20-29:

  1. Cellulitis (infection under the skin)

30-39:

  1. Cardiac death
  2. Cardiotoxicity (damage to the heart muscle)
  3. Drug abuse
  4. Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
  5. Muscle mass
  6. Myocardial fibrosis (a condition in which the heart's muscle cells are impaired)
  7. Testicular atrophy (wasting of testes)
  8. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  9. Anxiety
  10. Bradycardia (abnormally slow heart action)

40-49:

  1. Drug ineffective
  2. Anxiety
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Bone disorder
  5. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  6. Chest pain
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Death
  9. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  10. Dysgeusia (disorder of the sense of taste)

50-59:

  1. Influenza
  2. Lung infection
  3. Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
  4. Neoplasm malignant (cancer tumour)
  5. Tension headache
  6. Weight decreased
  7. Erectile dysfunction
  8. Head injury
  9. Hypotension (abnormally low blood pressure)
  10. Quality of life decreased

60+:

  1. Decreased appetite
  2. Pyrexia (fever)
  3. Head injury
  4. Infusion related reaction
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Nausea (feeling of having an urge to vomit)
  7. Sinus disorder (disease of sinus)
  8. Vomiting
  9. Pneumonia
  10. Death

What are the existing conditions these people have? *

  1. Depression: 13 people, 13.68%
  2. High Blood Pressure: 9 people, 9.47%
  3. Stress And Anxiety: 8 people, 8.42%
  4. Immunodeficiency Common Variable: 8 people, 8.42%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 7.37%
  6. Breakthrough Pain: 7 people, 7.37%
  7. Tremor (trembling or shaking movements in one or more parts of your body): 6 people, 6.32%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 6.32%
  9. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 6.32%
  10. Multiple Myeloma (cancer of the plasma cells): 6 people, 6.32%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Testosterone and Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Testosterone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Morphine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Testosterone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Morphine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on testosterone and morphine sulfate (the active ingredients of Testosterone and Morphine, respectively), and Testosterone and Morphine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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