Tetracycline hydrochloride and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tetracycline hydrochloride (tetracycline hydrochloride) and Codeine (codeine sulfate). Common drug interactions include visual impairment among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Tetracycline hydrochloride and Codeine. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Tetracycline hydrochloride?

Tetracycline hydrochloride has active ingredients of tetracycline hydrochloride. It is often used in acne. eHealthMe is studying from 790 Tetracycline hydrochloride users. Check the latest studies of Tetracycline hydrochloride.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.



On Jul, 13, 2026

59 people who take Tetracycline hydrochloride and Codeine together, and have interactions are studied.

Tetracycline hydrochloride and Codeine drug interactions.

What are the common drug interactions of Tetracycline Hydrochloride and Codeine, by gender? *:

female:

  1. Visual impairment
  2. Vomiting
  3. Wheezing (a high-pitched whistling sound made while you breath)
  4. Drug hypersensitivity
  5. Drug ineffective
  6. Drug intolerance (drug sensitivity)
  7. Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
  8. Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
  9. Arthralgia (joint pain)
  10. Joint swelling

male:

  1. Arthralgia (joint pain)
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Decreased appetite
  4. Discomfort
  5. Eructation (release of gas from the digestive tract)
  6. Feeling hot
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Middle insomnia (difficulty returning to sleep after awakening either in the middle of the night)
  9. Muscle spasms (muscle contraction)
  10. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Tetracycline Hydrochloride and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cough
  2. Drug hypersensitivity
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Dysphemia (stammering or stuttering)
  5. Speech disorder
  6. Abdominal discomfort
  7. Abdominal pain
  8. Angioedema (rapid swelling of the dermis)
  9. Asthma
  10. Blood pressure increased

40-49:

n/a

50-59:

  1. Arthralgia (joint pain)
  2. Drug hypersensitivity
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Blood magnesium decreased
  5. Drug level increased
  6. Fatigue (feeling of tiredness)
  7. Oedema peripheral (superficial swelling)
  8. Peripheral swelling
  9. Pyoderma gangrenosum (ulcerating condition of skin that results in heaped borders with a typical appearance)
  10. Weight increased

60+:

  1. Drug hypersensitivity
  2. Drug intolerance (drug sensitivity)
  3. Chest pain
  4. Dyspnoea (difficult or laboured respiration)
  5. Lip swelling
  6. Pruritus (severe itching of the skin)
  7. Swollen tongue (swelling of tongue)
  8. Throat tightness
  9. Urticaria (rash of round, red welts on the skin that itch intensely)
  10. Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 24 people, 40.68%
  2. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 22 people, 37.29%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 14 people, 23.73%
  4. Indigestion: 9 people, 15.25%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tetracycline hydrochloride and Codeine:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tetracycline hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Codeine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tetracycline hydrochloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Codeine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tetracycline hydrochloride and codeine sulfate (the active ingredients of Tetracycline hydrochloride and Codeine, respectively), and Tetracycline hydrochloride and Codeine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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