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Theo-24 and Accolate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Theo-24 (theophylline) and Accolate (zafirlukast). Common drug interactions include hot flushes among females and tinnitus among males.

The phase IV clinical study analyzes what interactions people have when they take Theo-24 and Accolate. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Theo-24?

Theo-24 has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 436 Theo-24 users. Check the latest studies of Theo-24.

What is Accolate?

Accolate has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 4,220 Accolate users. Check the latest studies of Accolate.

On Jul, 11, 2026

11 people who take Theo-24 and Accolate together, and have interactions are studied.

Theo-24 and Accolate drug interactions.

What are the common drug interactions of Theo-24 and Accolate, by gender? *:

female:

  1. Hot flushes (sudden feelings of heat)
  2. Rash pruritic (redness with itching)
  3. Upper respiratory tract infection
  4. Abdominal pain
  5. Arthralgia (joint pain)
  6. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  7. Cardiac discomfort
  8. Diabetic ulcer
  9. Drug dependence
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Tinnitus (a ringing in the ears)
  2. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  3. Cough
  4. Depressed level of consciousness
  5. Diarrhoea
  6. Hypertension (high blood pressure)
  7. Hypoxia (low oxygen in tissues)
  8. Vomiting

What are the common drug interactions of Theo-24 and Accolate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Arthralgia (joint pain)
  3. Eructation (release of gas from the digestive tract)
  4. Nausea (feeling of having an urge to vomit)
  5. Oesophagitis (inflammation of oesophagus)

40-49:

n/a

50-59:

  1. Cough
  2. Diabetic ulcer
  3. Drug effect decreased
  4. Dyspnoea (difficult or laboured respiration)
  5. Impaired healing
  6. Rash pruritic (redness with itching)
  7. Scratch

60+:

  1. Hot flushes (sudden feelings of heat)
  2. Tinnitus (a ringing in the ears)
  3. Hypoxia (low oxygen in tissues)
  4. Rash pruritic (redness with itching)
  5. Throat tightness
  6. Vomiting
  7. Weakness
  8. Upper respiratory tract infection
  9. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  10. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

What are the existing conditions these people have? *

  1. Pain: 1 person, 9.09%
  2. Intervertebral Disc Protrusion (spinal disc protrusion): 1 person, 9.09%
  3. Breakthrough Pain: 1 person, 9.09%
  4. Arthropathy: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Theo-24 and Accolate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Theo-24 and Accolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Theo-24:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Accolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Theo-24 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Accolate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on theophylline and zafirlukast (the active ingredients of Theo-24 and Accolate, respectively), and Theo-24 and Accolate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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