Theo-dur and Cipro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Theo-dur (theophylline) and Cipro (ciprofloxacin hydrochloride). Common drug interactions include constipation among females and dermatitis among males.
The phase IV clinical study analyzes what interactions people have when they take Theo-dur and Cipro. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.
What is Theo-dur?
Theo-dur has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 4,451 Theo-dur users. Check the latest studies of Theo-dur.
What is Cipro?
Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.
48 people who take Theo-dur and Cipro together, and have interactions are studied.

What are the common drug interactions of Theo-Dur and Cipro, by gender? *:
female:
- Constipation
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Cushingoid (obesity and weakening of the muscles)
- Dizziness
- Drug hypersensitivity
- Drug toxicity
- Eosinophil count increased
- Epstein-barr virus antibody positive
- Eyelid oedema (eyelids are swollen and contain excessive fluid)
- Gallbladder disorder
male:
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Colitis pseudomembranous (antibiotic-associated diarrhoea)
- Coma (state of unconsciousness lasting more than six hours)
- Confusion
- Diarrhoea
- Eye rolling
- Haematuria present (presence of blood in urine due to trauma)
- Hallucination (an experience involving the perception of something not present)
- Hypoaesthesia (reduced sense of touch or sensation)
- Nervousness
What are the common drug interactions of Theo-Dur and Cipro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Coma (state of unconsciousness lasting more than six hours)
- Hyperammonaemia
20-29:
n/a
30-39:
- Colitis pseudomembranous (antibiotic-associated diarrhoea)
- Ascites (accumulation of fluid in the abdominal cavity)
- Churg strauss syndrome (infection of small arteries and vein)
- Pericardial effusion (fluid around the heart)
- Pyrexia (fever)
- Rash erythematous (redness of the skin)
- Rheumatoid factor positive
- Rigors (an episode of shaking or exaggerated shivering)
- Abdominal pain
- Abdominal pain upper
40-49:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Haemorrhage (bleeding)
- Hepatic failure (liver failure)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Tinnitus (a ringing in the ears)
- Drug toxicity
- Headache (pain in head)
- Hepatitis (inflammation of the liver)
- Retching (strong involuntary effort to vomit)
- Urticaria (rash of round, red welts on the skin that itch intensely)
50-59:
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Gastrointestinal ulcer
- Gingivitis (inflammation of gums)
- Hearing impaired
- Hepatitis c
- Hepatitis chronic active
- Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Impaired gastric emptying
60+:
- Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
- Dyspnoea (difficult or laboured respiration)
- Coma (state of unconsciousness lasting more than six hours)
- Confusion
- Dysuria (painful or difficult urination)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Eye rolling
- Hallucination (an experience involving the perception of something not present)
- Nervousness
- Salivary hypersecretion (excess saliva secretion)
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Theo-dur and Cipro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Theo-dur:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cipro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Theo-dur and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cipro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on theophylline and ciprofloxacin hydrochloride (the active ingredients of Theo-dur and Cipro, respectively), and Theo-dur and Cipro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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