Theophylline and Naprosyn drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Theophylline (theophylline) and Naprosyn (naproxen). Common drug interactions include drug hypersensitivity among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Theophylline and Naprosyn. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Theophylline?
Theophylline has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 19,150 Theophylline users. Check the latest studies of Theophylline.
What is Naprosyn?
Naprosyn has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 16,738 Naprosyn users. Check the latest studies of Naprosyn.
41 people who take Theophylline and Naprosyn together, and have interactions are studied.

What are the common drug interactions of Theophylline and Naprosyn, by gender? *:
female:
- Drug hypersensitivity
- Drug screen positive
- Fall
- Osteoporosis (bones weak and more likely to break)
- Anger
- Crying
- Delusion (a false belief or opinion)
- Fatigue (feeling of tiredness)
- Glaucoma (increased fluid pressure in the eye with vision loss)
- Hepatitis (inflammation of the liver)
male:
- Dyspnoea (difficult or laboured respiration)
- Arthralgia (joint pain)
- Joint swelling
- Lower respiratory tract infection
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Neck pain
- Pain in limb
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
- Pseudomonas aeruginosa infection (p. aeruginosa cause of bacterial infections of the blood)
- Pulmonary congestion (congestion in the lungs)
What are the common drug interactions of Theophylline and Naprosyn, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anaphylactic reaction (serious allergic reaction)
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
- Dyspnoea (difficult or laboured respiration)
- Rash erythematous (redness of the skin)
- Rash pruritic (redness with itching)
40-49:
- Dehydration (dryness resulting from the removal of water)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Vomiting
- Pulmonary congestion (congestion in the lungs)
- Aortic valve calcification
- Cardiomegaly (increased size of heart than normal)
- Pulmonary oedema (fluid accumulation in the lungs)
- Spleen congestion (overloaded spleen)
- Contusion (a type of hematoma of tissue in which capillaries)
- Hepatic steatosis (fatty liver disease)
50-59:
- Drug hypersensitivity
- Muscle spasms (muscle contraction)
- Pain in extremity
60+:
- Dyspnoea (difficult or laboured respiration)
- Hip fracture
- Blood sodium increased
- Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)
- Decreased appetite
- Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
- Diarrhoea
- Disturbance in attention
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Epistaxis (bleed from the nose)
What are the existing conditions these people have? *
- Back Pain: 10 people, 24.39%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 12.20%
- Osteoporosis (bones weak and more likely to break): 4 people, 9.76%
- Insomnia (sleeplessness): 4 people, 9.76%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.32%
- Indigestion: 3 people, 7.32%
- High Blood Pressure: 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
Do you take Theophylline and Naprosyn?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Theophylline (19,150 reports)
- Naprosyn (16,738 reports)
Browse all drug interactions of Theophylline and Naprosyn:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Theophylline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Naprosyn:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Theophylline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Naprosyn and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
- Korang-Yeboah M, Rahman Z, Shah D, Mohammad A, Wu S, Siddiqui A, Khan MA, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International journal of pharmaceutics, 2016 Feb .
- Dhaval MK, "Impact of formulation and process variables on solid-state stability of theophylline in controlled release formulations", International Journal of Pharmaceutics, 2016 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on theophylline and naproxen (the active ingredients of Theophylline and Naprosyn, respectively), and Theophylline and Naprosyn (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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