Rituxan and Encephalitis - a phase IV clinical study of FDA data

Summary:

Encephalitis is reported as a side effect among people who take Rituxan (rituximab), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Azopt, and have Burkitt lymphoma.

The phase IV clinical study analyzes which people have Encephalitis when taking Rituxan. It is created by eHealthMe based on reports of 64,282 people who have side effects when taking Rituxan from the FDA, and is updated regularly.

What is Rituxan?

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. eHealthMe is studying from 64,791 Rituxan users. Check the latest studies of Rituxan.

What is Encephalitis?

Encephalitis (inflammation of the brain) is found to be associated with 663 drugs and 844 conditions by eHealthMe. Check the latest studies of Encephalitis.



On Jul, 12, 2026

64,282 people reported to have side effects when taking Rituxan.
Among them, 87 people (0.14%) have Encephalitis.

Could Rituxan cause Encephalitis?

Among these 87 people:

How long have people been on Rituxan when they have Encephalitis? *

  • < 1 month: 42.86 %
  • 1 - 6 months: 9.52 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 47.62 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Encephalitis when taking Rituxan? *

  • female: 67.95 %
  • male: 32.05 %

What is the age of people who have Encephalitis when taking Rituxan? *

  • 0-1: 0.0 %
  • 2-9: 3.17 %
  • 10-19: 0.0 %
  • 20-29: 7.94 %
  • 30-39: 4.76 %
  • 40-49: 19.05 %
  • 50-59: 17.46 %
  • 60+: 47.62 %

What are other drugs people take besides Rituxan? *

  1. Actemra: 31 people, 35.63%
  2. Arava: 31 people, 35.63%
  3. Azopt: 31 people, 35.63%
  4. Cymbalta: 28 people, 32.18%
  5. Synthroid: 28 people, 32.18%
  6. Ventolin: 26 people, 29.89%
  7. Xalatan: 26 people, 29.89%
  8. Coumadin: 25 people, 28.74%
  9. Nexium: 24 people, 27.59%
  10. Pantoprazole: 23 people, 26.44%

What are other side effects people have besides Encephalitis? *

  1. Joint Pain: 32 people, 36.78%
  2. Tremor (trembling or shaking movements in one or more parts of your body): 32 people, 36.78%
  3. Pain In Extremity: 31 people, 35.63%
  4. Heart Rate Decreased: 30 people, 34.48%
  5. Weakness: 30 people, 34.48%
  6. Fever: 30 people, 34.48%
  7. Malaise (a feeling of general discomfort or uneasiness): 29 people, 33.33%
  8. Fall: 29 people, 33.33%
  9. Back Pain: 29 people, 33.33%
  10. Pain: 29 people, 33.33%

What are the existing conditions these people have? *

  1. Burkitt Lymphoma (cancer of the lymphatic system): 7 people, 8.05%
  2. Encephalitis Autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain): 5 people, 5.75%
  3. Uveitis (inflammation of the uvea): 5 people, 5.75%
  4. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 5 people, 5.75%
  5. Pain: 3 people, 3.45%
  6. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 2 people, 2.30%
  7. High Blood Pressure: 2 people, 2.30%
  8. Muscle Spasms (muscle contraction): 2 people, 2.30%
  9. Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 2 people, 2.30%
  10. Juvenile Myoclonic Epilepsy (childhood epilepsy occurring early in morning affecting 12 to 18 years): 2 people, 2.30%

* Approximation only. Some reports may have incomplete information.

Do you take Rituxan and have Encephalitis?

- Check whether Encephalitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rituxan:

Encephalitis treatments and more:

How severe was Encephalitis and when was it recovered:

Expand to all the drugs that have ingredients of rituximab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rituxan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Encephalitis:

Browse all the conditions that are associated with Encephalitis:


How the study uses the data?

The study uses data from the FDA. It is based on rituximab (the active ingredients of Rituxan) and Rituxan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: