Fenofibrate and Application site pruritus - a phase IV clinical study of FDA data

Summary:

Application site pruritus is reported as a side effect among people who take Fenofibrate (fenofibrate), especially for people who are female, 60+ old, also take Metformin, and have Blood testosterone decreased.

The phase IV clinical study analyzes which people have Application site pruritus when taking Fenofibrate. It is created by eHealthMe based on reports of 39,402 people who have side effects when taking Fenofibrate from the FDA, and is updated regularly.

What is Fenofibrate?

Fenofibrate has active ingredients of fenofibrate. It is often used in high blood cholesterol. eHealthMe is studying from 40,456 Fenofibrate users. Check the latest studies of Fenofibrate.

What is Application site pruritus?

Application site pruritus (application site severe itching of the skin) is found to be associated with 549 drugs and 910 conditions by eHealthMe. Check the latest studies of Application site pruritus.

On Jul, 12, 2026

39,402 people reported to have side effects when taking Fenofibrate.
Among them, 21 people (0.05%) have Application site pruritus.

Could Fenofibrate cause Application site pruritus?

Among these 21 people:

What is the gender of people who have Application site pruritus when taking Fenofibrate? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Application site pruritus when taking Fenofibrate? *

What are other drugs people take besides Fenofibrate? *

Metformin: 4 people, 19.05%
Synthroid: 3 people, 14.29%
Valchlor: 3 people, 14.29%
Cymbalta: 3 people, 14.29%
Hctz: 3 people, 14.29%
Fentanyl Transdermal System: 3 people, 14.29%
Vitamin D: 2 people, 9.52%
Lyrica: 2 people, 9.52%
Nexium: 2 people, 9.52%
Amlodipine: 2 people, 9.52%

What are other side effects people have besides Application site pruritus? *

Application Site Erythema (redness of the skin at application site): 7 people, 33.33%
Application Site Rash: 6 people, 28.57%
Application Site Pain: 6 people, 28.57%
Rashes (redness): 4 people, 19.05%
Application Site Irritation: 2 people, 9.52%
Itching: 2 people, 9.52%
Application Site Warmth: 2 people, 9.52%
Sleep Disorder: 2 people, 9.52%
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure): 2 people, 9.52%
Application Site Vesicles (small bubble within a cell at application site): 1 person, 4.76%

What are the existing conditions these people have? *

Quit Smoking: 3 people, 14.29%
Blood Testosterone Decreased: 3 people, 14.29%
Hair Loss: 2 people, 9.52%
Pain: 2 people, 9.52%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 9.52%
Wound: 1 person, 4.76%
Blood Pressure Abnormal: 1 person, 4.76%
Cardiac Valve Disease (heart valve disease): 1 person, 4.76%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 4.76%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 4.76%

* Approximation only. Some reports may have incomplete information.

Do you take Fenofibrate and have Application site pruritus?

- Check whether Application site pruritus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fenofibrate:

Fenofibrate (40,456 reports)

Browse all side effects of Fenofibrate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site pruritus:

Application site pruritus (549 drugs)

Browse all the conditions that are associated with Application site pruritus:

Application site pruritus (910 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fenofibrate (the active ingredients of Fenofibrate) and Fenofibrate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.