Theophylline and Tracleer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Theophylline (theophylline) and Tracleer (bosentan). Common drug interactions include abdominal pain upper among females and respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Theophylline and Tracleer. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Theophylline?

Theophylline has active ingredients of theophylline. It is often used in asthma. eHealthMe is studying from 19,150 Theophylline users. Check the latest studies of Theophylline.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.

On Jul, 10, 2026

75 people who take Theophylline and Tracleer together, and have interactions are studied.

Theophylline and Tracleer drug interactions.

What are the common drug interactions of Theophylline and Tracleer, by gender? *:

female:

Abdominal pain upper
Constipation
Gallbladder disorder
Intestinal obstruction
Nausea (feeling of having an urge to vomit)
Poor quality sleep
Post procedural complication
Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
White blood cell count increased

male:

Respiratory failure (inadequate gas exchange by the respiratory system)
Dyspnoea (difficult or laboured respiration)
Cardiac arrest
Disease progression
Fall
Hypotension (abnormally low blood pressure)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Ventricular fibrillation (abnormally irregular heart rhythm)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematochezia (passage of stools containing blood)

What are the common drug interactions of Theophylline and Tracleer, by age (0-1 to 60+)? *:

0-1:

Respiratory failure (inadequate gas exchange by the respiratory system)

2-9:

n/a

10-19:

Dizziness
Syncope (loss of consciousness with an inability to maintain postural tone)

20-29:

n/a

30-39:

Chest discomfort
Colostomy
Cough
Dyspnoea (difficult or laboured respiration)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Respiratory distress (difficulty in breathing)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

40-49:

Dyspnoea (difficult or laboured respiration)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematochezia (passage of stools containing blood)
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Fatigue (feeling of tiredness)
Headache (pain in head)
Heart rate increased
Increased upper airway secretion
Rhinorrhoea (watery mucus discharge from the nose)

50-59:

Dyspnoea exertional (breathlessness or shortness of breath)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fatigue (feeling of tiredness)
Fungal infection
Gait disturbance
Haematochezia (passage of stools containing blood)
Headache (pain in head)
Heart rate increased
Hypersensitivity
Hypotension (abnormally low blood pressure)

60+:

Respiratory failure (inadequate gas exchange by the respiratory system)
Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Arthralgia (joint pain)
Delirium (wild excitement)
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)
Multi-organ failure (multisystem organ failure)
Restless legs syndrome (a powerful urge to move your legs)
Pyrexia (fever)

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 30 people, 40.00%
Heart Disease: 4 people, 5.33%

* Approximation only. Some reports may have incomplete information.

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