Thiamine and Lenvatinib drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Thiamine (thiamine (vitamin b1)) and Lenvatinib (lenvatinib). Common drug interactions include hepatic encephalopathy among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Thiamine and Lenvatinib. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Thiamine?

Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.

What is Lenvatinib?

Lenvatinib has active ingredients of lenvatinib. eHealthMe is studying from 3,587 Lenvatinib users. Check the latest studies of Lenvatinib.



On Aug, 04, 2026

30 people who take Thiamine and Lenvatinib together, and have interactions are studied.

Thiamine and Lenvatinib drug interactions.

What are the common drug interactions of Thiamine and Lenvatinib, by gender? *:

female:

  1. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  2. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  3. Epistaxis (bleed from the nose)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Contrast media reaction (reaction associated with the use of intravenous contrast material during radiology)
  6. Opsoclonus myoclonus (a rare neurological disorder of unknown causes which appears to be the result of an autoimmune process involving the nervous system)
  7. Anaemia (lack of blood)
  8. Angina pectoris (chest pain due to ischemia of the heart muscle)
  9. Diarrhoea
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Hypotension (abnormally low blood pressure)
  2. Anaemia (lack of blood)
  3. Hypertension (high blood pressure)
  4. Mucosal inflammation (infection of mucous membrane)
  5. Blood alkaline phosphatase increased
  6. Blood bilirubin increased
  7. Blood creatinine increased
  8. Glomerular filtration rate decreased
  9. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  10. Mastitis (inflammation of breast)

What are the common drug interactions of Thiamine and Lenvatinib, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anaemia (lack of blood)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  2. Anal abscess
  3. Anal fistula
  4. Hypokalaemia (low potassium)
  5. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  6. Hypotension (abnormally low blood pressure)
  7. Infection
  8. Nausea (feeling of having an urge to vomit)
  9. Hypertension (high blood pressure)
  10. Blood alkaline phosphatase increased

60+:

  1. Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
  2. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  3. Angina pectoris (chest pain due to ischemia of the heart muscle)
  4. Diarrhoea
  5. Dyspnoea (difficult or laboured respiration)
  6. Escherichia urinary tract infection (urinary tract infection by escherichia coli)
  7. Hyperkalaemia (damage to or disease of the kidney)
  8. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  9. Epistaxis (bleed from the nose)
  10. Rectal abscess (pus in rectum)

What are the existing conditions these people have? *

  1. Hepatocellular Carcinoma (liver cancer): 15 people, 50.00%
  2. Pain: 11 people, 36.67%
  3. Adverse Event: 5 people, 16.67%
  4. Nervous System Disorder (a general class of medical conditions affecting the nervous system): 3 people, 10.00%
  5. Nasopharyngeal Cancer (cancer of nasopharynx): 3 people, 10.00%
  6. Ascites (accumulation of fluid in the abdominal cavity): 3 people, 10.00%
  7. Renal Cell Carcinoma (a kidney cancer): 2 people, 6.67%
  8. Ovarian Cancer Recurrent (reoccurrence of ovary cancer): 2 people, 6.67%
  9. Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 2 people, 6.67%
  10. Folate Deficiency (lack of folic acid): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Thiamine and Lenvatinib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Thiamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lenvatinib:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Thiamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lenvatinib and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on thiamine (vitamin b1) and lenvatinib (the active ingredients of Thiamine and Lenvatinib, respectively), and Thiamine and Lenvatinib (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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