Tiazac and Evista drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tiazac (diltiazem hydrochloride) and Evista (raloxifene hydrochloride). Common drug interactions include acute myocardial infarction among females.

The phase IV clinical study analyzes what interactions people have when they take Tiazac and Evista. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Tiazac?

Tiazac has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 4,761 Tiazac users. Check the latest studies of Tiazac.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.



On Jul, 17, 2026

46 people who take Tiazac and Evista together, and have interactions are studied.

Tiazac and Evista drug interactions.

What are the common drug interactions of Tiazac and Evista, by gender? *:

female:

  1. Acute myocardial infarction (acute heart attack)
  2. Fibroma (tumours that are composed of fibrous or connective tissue)
  3. Lip and/or oral cavity cancer (cancer of lip or mouth)
  4. Loss of consciousness
  5. Pain
  6. Septic shock (shock due to blood infection)
  7. Angina pectoris (chest pain due to ischemia of the heart muscle)
  8. Body height decreased
  9. Breast pain
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

male:

n/a

What are the common drug interactions of Tiazac and Evista, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood glucose increased
  2. Drug ineffective

50-59:

  1. Dyspepsia (indigestion)
  2. Gastrointestinal irritation (irritation of stomach & intestine due to infection)
  3. Joint swelling
  4. Neoplasm growth accelerated (rapid growing tumour)
  5. Oedema lower limb (fluid collection in tissue of lower leg)
  6. Parotid gland enlargement
  7. Salivary gland neoplasm (tumour of salivary gland)
  8. Scar
  9. Skin papilloma (a general medical term for a tumour of the skin or mucous membrane with finger-like projections)
  10. Small cell lung cancer stage unspecified (lung cancer in unknown stage)

60+:

  1. Pneumonia
  2. Acute myocardial infarction (acute heart attack)
  3. Angina pectoris (chest pain due to ischemia of the heart muscle)
  4. Body height decreased
  5. Breast pain
  6. Glaucoma (increased fluid pressure in the eye with vision loss)
  7. Myalgia (muscle pain)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Renal atrophy (wasting of kidney)
  10. Upper respiratory tract infection

What are the existing conditions these people have? *

  1. Chest Pain: 5 people, 10.87%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 10.87%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.52%
  4. Joint Pain: 3 people, 6.52%
  5. Insomnia (sleeplessness): 3 people, 6.52%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 6.52%
  7. High Blood Cholesterol: 3 people, 6.52%
  8. Dry Skin: 3 people, 6.52%
  9. Arrhythmias (irregular heartbeat): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

Do you take Tiazac and Evista?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tiazac and Evista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tiazac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Evista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tiazac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Evista and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on diltiazem hydrochloride and raloxifene hydrochloride (the active ingredients of Tiazac and Evista, respectively), and Tiazac and Evista (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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