Tiazac and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tiazac (diltiazem hydrochloride) and Seroquel (quetiapine fumarate). Common drug interactions include vulvovaginal candidiasis among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Tiazac and Seroquel. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Tiazac?

Tiazac has active ingredients of diltiazem hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 4,761 Tiazac users. Check the latest studies of Tiazac.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,287 Seroquel users. Check the latest studies of Seroquel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

56 people who take Tiazac and Seroquel together, and have interactions are studied.

What are the common drug interactions of Tiazac and Seroquel, by gender? *:

female:

Vulvovaginal candidiasis (vulvovaginal infection by fungi)
Arthralgia (joint pain)
Back pain
Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
Neck pain
Pyrexia (fever)
Syncope (loss of consciousness with an inability to maintain postural tone)
Urinary tract infection
Blood glucose fluctuation
Chest discomfort

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Suicidal ideation
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Headache (pain in head)
Hypertensive heart disease
Hypokalaemia (low potassium)
Melaena (the passage of black, tarry stools)
Microcytic anaemia (a generic term for any type of anaemia characterized by small red blood cells)
Polysubstance dependence
Renal failure chronic (long lasting kidney dysfunction)

What are the common drug interactions of Tiazac and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Adverse drug reaction
Blood cholesterol increased
Blood triglycerides increased
Death
Diabetic coma
Diabetic complication
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Disease progression
Hyperlipidaemia (presence of excess lipids in the blood)
Obesity (having too much body fat)

30-39:

Abscess limb (limb infection)
Alcohol abuse
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure chronic
Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
Drug dependence
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

40-49:

Type 2 diabetes mellitus
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pancreatitis (inflammation of pancreas)
Cough
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Staphylococcal infection (an infection with staphylococcus bacteria)
Pancreatitis acute (sudden inflammation of pancreas)
Depressed mood

50-59:

Sensation of foreign body
Vocal cord polyp
Insulin resistant diabetes
Neuropathy peripheral (surface nerve damage)
Androgenetic alopecia (common form of hair loss)
Delusion (a false belief or opinion)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hip fracture
Hyperglycaemia (high blood sugar)
Hypotension (abnormally low blood pressure)

60+:

Dyspnoea (difficult or laboured respiration)
Hypotension (abnormally low blood pressure)
Fall
Fluid retention (an abnormal accumulation of fluid in the blood)
Headache (pain in head)
Localised oedema (fluid retention in a particular part of the body)
Oropharyngeal pain
Pneumonia
Productive cough
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

Depression: 23 people, 41.07%
Sleep Disorder: 9 people, 16.07%
Stress And Anxiety: 7 people, 12.50%
Quit Smoking: 6 people, 10.71%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 8.93%
Pain: 5 people, 8.93%
Dyspnea (difficult or laboured breathing): 5 people, 8.93%
Insomnia (sleeplessness): 4 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.14%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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