Tigan and Dexilant drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tigan (trimethobenzamide hydrochloride) and Dexilant (dexlansoprazole). Common drug interactions include chronic kidney disease among females and accidental exposure among males.

The phase IV clinical study analyzes what interactions people have when they take Tigan and Dexilant. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Tigan?

Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,904 Tigan users. Check the latest studies of Tigan.

What is Dexilant?

Dexilant has active ingredients of dexlansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 57,103 Dexilant users. Check the latest studies of Dexilant.

On Jul, 27, 2026

14 people who take Tigan and Dexilant together, and have interactions are studied.

What are the common drug interactions of Tigan and Dexilant, by gender? *:

female:

Chronic kidney disease
Infection
Middle ear effusion (fluid in middle ear)
Pyrexia (fever)
Road traffic accident
Sinus disorder (disease of sinus)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Upper respiratory tract infection
Death

male:

Accidental exposure
Dysarthria (speech disorder)
Intestinal stenosis (partial obstruction that causes the centre opening of the intestine to become narrower)
Lip haemorrhage (bleeding lip)
Fall
Hypersomnia (excessive daytime sleepiness (eds))
Lip injury
Memory impairment
Mouth injury
Gastrointestinal inflammation (inflammation of stomach and intestine)

What are the common drug interactions of Tigan and Dexilant, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Accidental exposure
Dysarthria (speech disorder)
Fall
Hypersomnia (excessive daytime sleepiness (eds))
Lip injury
Memory impairment
Mouth injury
Haemorrhage (bleeding)
Lip haemorrhage (bleeding lip)

50-59:

Infection
Middle ear effusion (fluid in middle ear)
Pyrexia (fever)
Road traffic accident
Sinus disorder (disease of sinus)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Upper respiratory tract infection
Cellulitis (infection under the skin)
Hospitalisation

60+:

Chronic kidney disease
Death
Hypertension (high blood pressure)
Muscular weakness (muscle weakness)
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pain
Throat irritation
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 6 people, 42.86%
High Blood Cholesterol: 3 people, 21.43%
Immune System Disorder: 2 people, 14.29%
Gout (uric acid crystals building up in the body): 2 people, 14.29%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 2 people, 14.29%
Oedema (fluid collection in tissue): 2 people, 14.29%
Spinal Compression Fracture (fracture due to spinal compression on bone): 1 person, 7.14%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 7.14%
Heart Attack: 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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