Tigan and Diazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tigan (trimethobenzamide hydrochloride) and Diazepam (diazepam). Common drug interactions include arthropathy among females and drug toxicity among males.

The phase IV clinical study analyzes what interactions people have when they take Tigan and Diazepam. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Tigan?

Tigan has active ingredients of trimethobenzamide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,904 Tigan users. Check the latest studies of Tigan.

What is Diazepam?

Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

32 people who take Tigan and Diazepam together, and have interactions are studied.

What are the common drug interactions of Tigan and Diazepam, by gender? *:

female:

Arthropathy
Ascites (accumulation of fluid in the abdominal cavity)
Asthma
Back injury
Balance disorder
Blood pressure increased
Blood thyroid stimulating hormone abnormal
Blood thyroid stimulating hormone decreased
Blood thyroid stimulating hormone increased
Blood triglycerides increased

male:

Drug toxicity
Coma (state of unconsciousness lasting more than six hours)
Dyskinesia (abnormality or impairment of voluntary movement)
Eating disorder
Hepatocellular damage (liver damage)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Inflammation
Liver disorder (liver diseases)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Neck pain

What are the common drug interactions of Tigan and Diazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Rigors (an episode of shaking or exaggerated shivering)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)

30-39:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Infection
Injection site cellulitis (injection site inflammation)
Injection site extravasation (flow of (blood or lymph) from injection site)
Joint dislocation (a joint position is changed from normal position)
Lupus encephalitis (a chronic inflammatory autoimmune disorder that may affect brain)
Spinal compression fracture (fracture due to spinal compression on bone)
Upper limb fracture

40-49:

Drug dependence
Abdominal pain upper
Anaemia (lack of blood)
Asthma
Back injury
Back pain
Diarrhoea
Drug ineffective
Injection site bruising
Injection site pain

50-59:

Myalgia (muscle pain)
Pulse absent
Cardiac arrest
Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)
Influenza
Laryngitis (inflammation of the larynx)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Drug toxicity
Eye rolling
Haemoglobin decreased

60+:

Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic failure (liver failure)
Renal tubular necrosis (death of kidney tubules)
Urinary bladder haemorrhage (urinary bladder bleeding)
Vertigo
Cardiac disorder
Colonic haemorrhage (bleeding in colon)
Constipation
Drug eruption (adverse drug reaction of the skin)
Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

Nausea And Vomiting: 7 people, 21.88%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 18.75%
Depression: 6 people, 18.75%
Asthma: 5 people, 15.62%
Migraine (headache): 4 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 12.50%
Gastric Ulcer (stomach ulcer): 4 people, 12.50%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 3 people, 9.38%
Muscle Spasms (muscle contraction): 3 people, 9.38%
Hypersensitivity: 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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