Timoptic and Centrum drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Timoptic (timolol maleate) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include full blood count decreased among females and pain among males.
The phase IV clinical study analyzes what interactions people have when they take Timoptic and Centrum. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Timoptic?
Timoptic has active ingredients of timolol maleate. It is often used in glaucoma. eHealthMe is studying from 4,247 Timoptic users. Check the latest studies of Timoptic.
What is Centrum?
Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.
41 people who take Timoptic and Centrum together, and have interactions are studied.

What are the common drug interactions of Timoptic and Centrum, by gender? *:
female:
- Full blood count decreased
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gingival bleeding (bleeding gums)
- Haemorrhage (bleeding)
- Hallucination (an experience involving the perception of something not present)
- Hot flush (sudden feelings of heat)
- Hypercholesterolaemia (high levels of cholesterol in the blood)
- Hypertension (high blood pressure)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Infection
male:
- Pain
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Collapse (sudden functional breakdown)
- Conjunctival hyperaemia (congestion of conjunctival vessels)
- Death
- Diarrhoea
- Dizziness
- Drug ineffective
- Encephalopathy (functioning of the brain is affected by some agent or condition)
What are the common drug interactions of Timoptic and Centrum, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Memory impairment
- Menopause (end of monthly cycles in women)
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
- Visual acuity reduced (reduced clearness of vision)
- Chest pain
- Depression
- Dyspnoea (difficult or laboured respiration)
- Injection site pain
60+:
- Constipation
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Chest pain
- Contusion (a type of hematoma of tissue in which capillaries)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Coronary artery stenosis (narrowing of coronary artery)
- Depression
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Erythema (redness of the skin)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 12.20%
- Multiple Myeloma (cancer of the plasma cells): 5 people, 12.20%
- High Blood Pressure: 5 people, 12.20%
- Pain: 4 people, 9.76%
- High Blood Cholesterol: 4 people, 9.76%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 7.32%
- Diabetes: 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
Do you take Timoptic and Centrum?
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- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Timoptic and Centrum:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Timoptic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Centrum:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Timoptic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Centrum and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on timolol maleate and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Timoptic and Centrum, respectively), and Timoptic and Centrum (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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