Timoptic and Digoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Timoptic (timolol maleate) and Digoxin (digoxin). Common drug interactions include gout among females and gastritis among males.

The phase IV clinical study analyzes what interactions people have when they take Timoptic and Digoxin. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Timoptic?

Timoptic has active ingredients of timolol maleate. It is often used in glaucoma. eHealthMe is studying from 4,247 Timoptic users. Check the latest studies of Timoptic.

What is Digoxin?

Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.



On Jul, 20, 2026

77 people who take Timoptic and Digoxin together, and have interactions are studied.

Timoptic and Digoxin drug interactions.

What are the common drug interactions of Timoptic and Digoxin, by gender? *:

female:

  1. Gout (uric acid crystals building up in the body)
  2. Arrhythmia (irregular heartbeat)
  3. Dyslipidaemia (abnormal amount of lipids)
  4. Fatigue (feeling of tiredness)
  5. Renal failure (kidney dysfunction)
  6. Asthenia (weakness)
  7. Bradycardia (abnormally slow heart action)
  8. Depression
  9. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  10. Diarrhoea

male:

  1. Gastritis (inflammation of stomach)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Hypertension (high blood pressure)
  4. Renal cyst (kidney cyst)
  5. Arrhythmia (irregular heartbeat)
  6. Back pain
  7. Confusional state
  8. Cough
  9. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  10. Abscess (pus)

What are the common drug interactions of Timoptic and Digoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anxiety
  2. Colon cancer
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Weight decreased
  5. Sinusitis (inflammation of sinus)
  6. Urinary tract infection

50-59:

  1. Atrioventricular block first degree (heart block first degree)
  2. Atrioventricular block second degree (heart block second degree)
  3. Bradycardia (abnormally slow heart action)
  4. Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
  5. Breast cancer metastatic
  6. Cardioactive drug level decreased
  7. Carotid artery stenosis (narrowing of carotid artery)
  8. Chest discomfort
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Cough

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Hypertension (high blood pressure)
  3. Chest discomfort
  4. Decreased appetite
  5. Gout (uric acid crystals building up in the body)
  6. Coma (state of unconsciousness lasting more than six hours)
  7. Fall
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Subdural haematoma (blood collects between the skull and the surface of the brain)
  10. Cardiac disorder

* Approximation only. Some reports may have incomplete information.

Do you take Timoptic and Digoxin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Timoptic and Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Timoptic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Digoxin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Timoptic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Digoxin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on timolol maleate and digoxin (the active ingredients of Timoptic and Digoxin, respectively), and Timoptic and Digoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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