Tivicay and Trulicity drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tivicay (dolutegravir sodium) and Trulicity (dulaglutide). Common drug interactions include anhedonia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Tivicay and Trulicity. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Tivicay?

Tivicay has active ingredients of dolutegravir sodium. It is often used in hiv infection. eHealthMe is studying from 9,674 Tivicay users. Check the latest studies of Tivicay.

What is Trulicity?

Trulicity has active ingredients of dulaglutide. It is often used in weight loss. eHealthMe is studying from 77,529 Trulicity users. Check the latest studies of Trulicity.

On Jul, 25, 2026

33 people who take Tivicay and Trulicity together, and have interactions are studied.

Tivicay and Trulicity drug interactions.

What are the common drug interactions of Tivicay and Trulicity, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Emotional distress
Pain
Renal impairment (severely reduced kidney function)
Chronic kidney disease
Ankle fracture
Depression
Gait disturbance

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Hyperlipidaemia (presence of excess lipids in the blood)
Abdominal discomfort
Anaemia (lack of blood)
Blood creatinine increased
Depression
Drug resistance (reduction in effectiveness of a drug)
Joint injury
Malaise (a feeling of general discomfort or uneasiness)

What are the common drug interactions of Tivicay and Trulicity, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abscess limb (limb infection)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Chronic kidney disease
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Orchitis (inflammation of the testes)
Scrotal abscess (pus in scrotum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Chronic kidney disease
Emotional distress
Pain
Tooth loss
Blood creatinine increased
Bone loss
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

40-49:

Drug resistance (reduction in effectiveness of a drug)
Hyperlipidaemia (presence of excess lipids in the blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Bone density decreased
Emotional distress
Fatigue (feeling of tiredness)
Gait disturbance
Insomnia (sleeplessness)

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Chronic kidney disease
Anaemia (lack of blood)
Bone density decreased
Depression
Abdominal discomfort
Fatigue (feeling of tiredness)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Mobility decreased (ability to move is reduced)
Renal failure (kidney dysfunction)
Death
Decreased activity
Depression
Fatigue (feeling of tiredness)
Osteoporosis (bones weak and more likely to break)
Proteinuria (presence of protein in the urine)

What are the existing conditions these people have? *

Renal Cell Carcinoma (a kidney cancer): 4 people, 12.12%
Lipodystrophy Acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired): 3 people, 9.09%
Diabetes: 3 people, 9.09%
Type 2 Diabetes: 2 people, 6.06%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 6.06%
Gastric Disorder (disease of stomach): 2 people, 6.06%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 6.06%
Depression: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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