Tobrex and Fluconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Tobrex (tobramycin) and Fluconazole (fluconazole). Common drug interactions include ascites among females and acute respiratory distress syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Tobrex and Fluconazole. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Tobrex?

Tobrex has active ingredients of tobramycin. eHealthMe is studying from 762 Tobrex users. Check the latest studies of Tobrex.

What is Fluconazole?

Fluconazole has active ingredients of fluconazole. It is often used in vaginal yeast infection. eHealthMe is studying from 70,481 Fluconazole users. Check the latest studies of Fluconazole.



On Jul, 20, 2026

21 people who take Tobrex and Fluconazole together, and have interactions are studied.

Tobrex and Fluconazole drug interactions.

What are the common drug interactions of Tobrex and Fluconazole, by gender? *:

female:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Cardiac arrest
  3. Exomphalos (weakness of the baby's abdominal wall where the umbilical cord joins it)
  4. Growth retardation (delayed growth)
  5. Heart rate decreased
  6. Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
  7. Hyperglycaemia (high blood sugar)
  8. Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
  9. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  10. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)

male:

  1. Acute respiratory distress syndrome
  2. Chronic kidney disease
  3. Colitis (inflammation of colon)
  4. Disease progression
  5. Influenza
  6. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  7. Pneumonia adenoviral (viral pneumonia caused by an adenovirus)
  8. Renal failure (kidney dysfunction)
  9. Renal impairment (severely reduced kidney function)

What are the common drug interactions of Tobrex and Fluconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Acute respiratory distress syndrome
  2. Disease progression
  3. Influenza
  4. Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
  5. Pneumonia adenoviral (viral pneumonia caused by an adenovirus)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Colitis (inflammation of colon)

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Renal impairment (severely reduced kidney function)

60+:

  1. Chronic kidney disease
  2. Death
  3. Micturition urgency (urgency to pass the urine)
  4. Nephropathy (damage to or disease of a kidney)
  5. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  6. Polyuria (production of too much dilute urine)
  7. Proteinuria (presence of protein in the urine)
  8. Pyelocaliectasis
  9. Renal atrophy (wasting of kidney)
  10. Hyperkalaemia (damage to or disease of the kidney)

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 13 people, 61.90%
  2. Conjunctivitis (pink eye): 13 people, 61.90%
  3. Sinusitis (inflammation of sinus): 13 people, 61.90%
  4. Stress And Anxiety: 12 people, 57.14%
  5. Depression: 11 people, 52.38%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 23.81%
  7. Pain: 4 people, 19.05%
  8. High Blood Pressure: 4 people, 19.05%
  9. Eye Infection: 4 people, 19.05%
  10. Hypersensitivity: 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

Do you take Tobrex and Fluconazole?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Tobrex and Fluconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Tobrex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fluconazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tobrex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fluconazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tobramycin and fluconazole (the active ingredients of Tobrex and Fluconazole, respectively), and Tobrex and Fluconazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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