Fentanyl and Myoglobinuria - a phase IV clinical study of FDA data

Summary:

Myoglobinuria is reported as a side effect among people who take Fentanyl (fentanyl citrate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sevoflurane, and have Anaesthesia.

The phase IV clinical study analyzes which people have Myoglobinuria when taking Fentanyl. It is created by eHealthMe based on reports of 72,646 people who have side effects when taking Fentanyl from the FDA, and is updated regularly.

What is Fentanyl?

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 73,301 Fentanyl users. Check the latest studies of Fentanyl.

What is Myoglobinuria?

Myoglobinuria (presence of myoglobin in the urine) is found to be associated with 112 drugs and 213 conditions by eHealthMe. Check the latest studies of Myoglobinuria.

On Jul, 20, 2026

72,646 people reported to have side effects when taking Fentanyl.
Among them, 15 people (0.02%) have Myoglobinuria.

Among these 15 people:

How long have people been on Fentanyl when they have Myoglobinuria? *

What is the gender of people who have Myoglobinuria when taking Fentanyl? *

female: 26.67 %
male: 73.33 %

What is the age of people who have Myoglobinuria when taking Fentanyl? *

What are other drugs people take besides Fentanyl? *

Sevoflurane: 9 people, 60.00%
Vecuronium Bromide: 7 people, 46.67%
Propofol: 7 people, 46.67%
Zantac: 3 people, 20.00%
Diprivan: 3 people, 20.00%
Nitrous Oxide W/ Oxygen: 3 people, 20.00%
Atarax: 2 people, 13.33%
Ketalar: 2 people, 13.33%
Rocuronium Bromide: 1 person, 6.67%
Remifentanil Hydrochloride: 1 person, 6.67%

What are other side effects people have besides Myoglobinuria? *

Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 9 people, 60.00%
Blood Creatine Phosphokinase Increased: 7 people, 46.67%
Myoglobin Blood Increased (presence of myoglobin in blood increased): 5 people, 33.33%
Hyperkalemia (damage to or disease of the kidney): 4 people, 26.67%
Haematuria (presence of blood in urine): 3 people, 20.00%
Acute Kidney Failure: 2 people, 13.33%
Hyperpyrexia Malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions- infectious): 2 people, 13.33%
Heart Rate Increased: 2 people, 13.33%
Hyperthermia Malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions): 2 people, 13.33%
Aspartate Aminotransferase Increased: 2 people, 13.33%

What are the existing conditions these people have? *

Anaesthesia: 4 people, 26.67%
Sedation: 2 people, 13.33%
Haemorrhage (bleeding): 2 people, 13.33%
Liver Disorder (liver diseases): 1 person, 6.67%
High Blood Pressure: 1 person, 6.67%
General Anaesthesia: 1 person, 6.67%
Analgesia: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Fentanyl and have Myoglobinuria?

- Check whether Myoglobinuria is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fentanyl:

Fentanyl (73,301 reports)

Myoglobinuria treatments and more:

Myoglobinuria (830 reports)

Browse all side effects of Fentanyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Myoglobinuria:

Myoglobinuria (112 drugs)

Browse all the conditions that are associated with Myoglobinuria:

Myoglobinuria (213 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fentanyl citrate (the active ingredients of Fentanyl) and Fentanyl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.