Topamax and Bactroban drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Bactroban (mupirocin). Common drug interactions include diarrhoea among females and respiratory tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Bactroban. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

What is Bactroban?

Bactroban has active ingredients of mupirocin. It is often used in infection. eHealthMe is studying from 4,967 Bactroban users. Check the latest studies of Bactroban.



On Jul, 25, 2026

88 people who take Topamax and Bactroban together, and have interactions are studied.

Topamax and Bactroban drug interactions.

What are the common drug interactions of Topamax and Bactroban, by gender? *:

female:

  1. Diarrhoea
  2. Sinusitis (inflammation of sinus)
  3. Abasia (inability to walk)
  4. Back pain
  5. Blood potassium decreased
  6. Burns second degree
  7. Fluid retention (an abnormal accumulation of fluid in the blood)
  8. Gangrene (body tissue dies)
  9. Hypersomnia (excessive daytime sleepiness (eds))
  10. Pyrexia (fever)

male:

  1. Respiratory tract infection
  2. Acute sinusitis
  3. Nausea (feeling of having an urge to vomit)
  4. Oedema peripheral (superficial swelling)
  5. Body temperature fluctuation
  6. Confusional state
  7. Lung disorder (lung disease)
  8. Pneumonia
  9. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Topamax and Bactroban, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Alanine aminotransferase decreased
  2. Blood pressure diastolic decreased
  3. Blood thyroid stimulating hormone increased
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Erythema multiforme (a type of hypersensitivity reaction)
  6. Face oedema (swelling of face)
  7. Hypertension (high blood pressure)
  8. Oedema peripheral (superficial swelling)
  9. Weight increased

10-19:

  1. Hypersomnia (excessive daytime sleepiness (eds))
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Abdominal discomfort
  4. Diarrhoea
  5. Nausea (feeling of having an urge to vomit)
  6. Adverse drug reaction
  7. Hypophagia (reduced food intake)

20-29:

  1. Weight increased
  2. Catheter site haemorrhage (bleeding at catheter site)
  3. Depressed mood
  4. Drug hypersensitivity
  5. Ear infection
  6. Intestinal obstruction
  7. Osteoporosis (bones weak and more likely to break)
  8. Pyrexia (fever)
  9. Respiratory tract infection
  10. Respiratory tract infection viral

30-39:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Coma (state of unconsciousness lasting more than six hours)
  3. Blood pressure decreased
  4. Heart rate decreased
  5. Hypersensitivity
  6. Impaired healing
  7. Limb injury
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Weight decreased
  10. Weight increased

40-49:

  1. Abasia (inability to walk)
  2. Blood potassium decreased
  3. Burns second degree
  4. Fluid retention (an abnormal accumulation of fluid in the blood)
  5. Gangrene (body tissue dies)
  6. Oedema peripheral (superficial swelling)
  7. Weight decreased
  8. Weight increased
  9. Headache (pain in head)
  10. Chronic kidney disease

50-59:

  1. Chronic kidney disease
  2. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  3. Decreased appetite
  4. Decreased interest
  5. Depression
  6. Drug hypersensitivity
  7. Dry mouth
  8. Dysuria (painful or difficult urination)
  9. Eructation (release of gas from the digestive tract)
  10. Fall

60+:

  1. Hypertension (high blood pressure)
  2. Headache (pain in head)
  3. Fatigue (feeling of tiredness)
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Keratitis (eye's cornea, the front part of the eye, becomes inflamed)
  6. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  7. Rash
  8. Urinary tract infection
  9. Abdominal distension
  10. Abdominal pain upper

What are the existing conditions these people have? *

  1. Pain: 16 people, 18.18%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 15 people, 17.05%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 15.91%
  4. Immunodeficiency Common Variable: 11 people, 12.50%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 12.50%
  6. Depression: 11 people, 12.50%
  7. Asthma: 9 people, 10.23%
  8. Stress And Anxiety: 9 people, 10.23%
  9. Inflammation: 8 people, 9.09%
  10. High Blood Cholesterol: 8 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Topamax and Bactroban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bactroban:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topamax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bactroban and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on topiramate and mupirocin (the active ingredients of Topamax and Bactroban, respectively), and Topamax and Bactroban (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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