Topamax and Everolimus drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Topamax (topiramate) and Everolimus (everolimus). Common drug interactions include retinal disorder among females and seizure among males.
The phase IV clinical study analyzes what interactions people have when they take Topamax and Everolimus. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Topamax?
Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.
What is Everolimus?
Everolimus has active ingredients of everolimus. eHealthMe is studying from 16,228 Everolimus users. Check the latest studies of Everolimus.
11 people who take Topamax and Everolimus together, and have interactions are studied.

What are the common drug interactions of Topamax and Everolimus, by gender? *:
female:
- Retinal disorder (disease of retina)
- Constipation
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Fall
- Internal injury
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
- Somnolence (a state of near-sleep, a strong desire for sleep)
male:
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Blood glucose decreased
- Seizure cluster (small group of seizure)
- Sinusitis (inflammation of sinus)
- Stomatitis (inflammation of mucous membrane of mouth)
- Craniocerebral injury (injury to cranium and brain)
- Fall
- Hypertension (high blood pressure)
- Altered state of consciousness (altered state of mind)
- Anaemia (lack of blood)
What are the common drug interactions of Topamax and Everolimus, by age (0-1 to 60+)? *:
0-1:
- Anaemia (lack of blood)
- Neutropenia (an abnormally low number of neutrophils)
- Stomatitis (inflammation of mucous membrane of mouth)
2-9:
n/a
10-19:
- Seizure cluster (small group of seizure)
- Retinal disorder (disease of retina)
- Altered state of consciousness (altered state of mind)
20-29:
- Fall
- Infusion site pruritus (severe itching at infusion site)
- Infusion site urticaria (rash of round, red welts on the skin at infusion site)
- Internal injury
- Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
- Sinusitis (inflammation of sinus)
- Somnolence (a state of near-sleep, a strong desire for sleep)
30-39:
n/a
40-49:
n/a
50-59:
- Constipation
60+:
n/a
What are the existing conditions these people have? *
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 5 people, 45.45%
- Partial Seizures (seizures which affect only a part of the brain at onset): 2 people, 18.18%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 18.18%
- Tuberous Sclerosis (a rare genetic disease that causes benign tumours to grow in the brain and other organs): 1 person, 9.09%
- Immunodeficiency: 1 person, 9.09%
- Colon Cancer: 1 person, 9.09%
- Angiomyolipoma (most common benign tumour of the kidney): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Topamax and Everolimus?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Topamax (58,954 reports)
- Everolimus (16,228 reports)
Browse all drug interactions of Topamax and Everolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Topamax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Everolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Topamax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Everolimus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on topiramate and everolimus (the active ingredients of Topamax and Everolimus, respectively), and Topamax and Everolimus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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