Topamax and Maxair drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Maxair (pirbuterol acetate). Common drug interactions include blood pressure increased among females and biliary dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Maxair. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,955 Topamax users. Check the latest studies of Topamax.

What is Maxair?

Maxair has active ingredients of pirbuterol acetate. It is often used in asthma. eHealthMe is studying from 2,903 Maxair users. Check the latest studies of Maxair.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

61 people who take Topamax and Maxair together, and have interactions are studied.

What are the common drug interactions of Topamax and Maxair, by gender? *:

female:

Blood pressure increased
Cataract (clouding of the lens inside the eye)
Overdose
Dehydration (dryness resulting from the removal of water)
Hereditary angioedema (recurrent episodes of severe swelling)
Abdominal pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Pulmonary embolism (blockage of the main artery of the lung)
Vomiting

male:

Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Emotional distress
Gallbladder disorder
General physical health deterioration (weak health status)
Injury
Pain
Postoperative adhesion
Hereditary angioedema (recurrent episodes of severe swelling)
Interstitial lung disease

What are the common drug interactions of Topamax and Maxair, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blindness night
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Eye disorder
Herpes zoster
Optic nerve disorder (disease of optic nerve)
Visual field defect

30-39:

Constipation
Dyspnoea exertional (breathlessness or shortness of breath)
Pulmonary embolism (blockage of the main artery of the lung)
Seasonal allergy (allergic condition due to certain season)
Urinary tract infection
Cough
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Hypercoagulation (increased tendency for clotting of the blood)

40-49:

Blood pressure increased
Cataract (clouding of the lens inside the eye)
Overdose
Sinusitis (inflammation of sinus)
Dehydration (dryness resulting from the removal of water)
Hereditary angioedema (recurrent episodes of severe swelling)
Vomiting
Headache (pain in head)
Abdominal discomfort
Abdominal pain

50-59:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Coronary artery stenosis (narrowing of coronary artery)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Thrombosis (formation of a blood clot inside a blood vessel)
Ear infection
Eye haemorrhage (bleeding in the eye)
Eye swelling
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Lymphadenopathy (disease or enlargement of lymph nodes)

60+:

Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Emotional distress
Disturbance in attention
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Dyspnoea (difficult or laboured respiration)
Hereditary angioedema (recurrent episodes of severe swelling)
Injection site haemorrhage (bleeding from injection site)
Injection site mass
Injection site pain
Interstitial lung disease

What are the existing conditions these people have? *

Fibromyalgia (a long-term condition which causes pain all over the body): 17 people, 27.87%
Pain: 14 people, 22.95%
Nausea (feeling of having an urge to vomit): 11 people, 18.03%
Hereditary Angioedema (recurrent episodes of severe swelling): 10 people, 16.39%
Seasonal Allergy (allergic condition due to certain season): 9 people, 14.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 11.48%
Hypersensitivity: 6 people, 9.84%
Stress And Anxiety: 5 people, 8.20%
Back Pain: 5 people, 8.20%
Sinusitis (inflammation of sinus): 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

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