Topamax and Novolin r drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Topamax (topiramate) and Novolin r (insulin recombinant purified human). Common drug interactions include cataract among females and atelectasis among males.
The phase IV clinical study analyzes what interactions people have when they take Topamax and Novolin r. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Topamax?
Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.
What is Novolin r?
Novolin r has active ingredients of insulin recombinant purified human. It is often used in type 1 diabetes. eHealthMe is studying from 4,568 Novolin r users. Check the latest studies of Novolin r.
12 people who take Topamax and Novolin r together, and have interactions are studied.

What are the common drug interactions of Topamax and Novolin R, by gender? *:
female:
- Cataract (clouding of the lens inside the eye)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Diarrhoea
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Nausea (feeling of having an urge to vomit)
- Parkinson's disease
- Rash
- Urticaria (rash of round, red welts on the skin that itch intensely)
male:
- Atelectasis (partial or complete collapse of the lung)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Multiple injuries
- Renal failure acute (rapid kidney dysfunction)
- Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
- Sinusitis (inflammation of sinus)
What are the common drug interactions of Topamax and Novolin R, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Headache (pain in head)
- Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
- Obesity (having too much body fat)
- Type 2 diabetes mellitus
20-29:
- Abdominal pain
- Acute sinusitis
- Adjustment disorder with mixed anxiety and depressed mood
- Asthenia (weakness)
- Atelectasis (partial or complete collapse of the lung)
- Back pain
- Bipolar disorder (mood disorder)
- Borderline personality disorder
- Chest pain
- Dental caries
30-39:
- Blood cholesterol increased
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Hyperlipidaemia (presence of excess lipids in the blood)
- Obesity (having too much body fat)
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
40-49:
n/a
50-59:
- Cataract (clouding of the lens inside the eye)
- Diarrhoea
- Drug hypersensitivity
- Nausea (feeling of having an urge to vomit)
- Parkinson's disease
- Rash
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Vomiting
- Adverse drug reaction
60+:
- Chronic kidney disease
- Renal injury (kidney injury)
- Vocal cord paralysis
- Anaemia (lack of blood)
- Arteriovenous malformation
- Cardiac failure congestive
- Dyspnoea (difficult or laboured respiration)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Infection
- Nephrogenic anaemia (anaemia due to kidney disease)
What are the existing conditions these people have? *
- Depression: 6 people, 50.00%
- Cardiac Disorder: 4 people, 33.33%
- High Blood Pressure: 3 people, 25.00%
- High Blood Cholesterol: 3 people, 25.00%
- Bipolar Disorder (mood disorder): 3 people, 25.00%
- Cardiac Failure Congestive: 3 people, 25.00%
- Pain: 3 people, 25.00%
- Diabetes: 3 people, 25.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
- Stress And Anxiety: 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Topamax and Novolin r?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Topamax and Novolin r:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Topamax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Novolin r:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Topamax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Novolin r and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on topiramate and insulin recombinant purified human (the active ingredients of Topamax and Novolin r, respectively), and Topamax and Novolin r (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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