Topamax and Tambocor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Tambocor (flecainide acetate). Common drug interactions include cerebral atrophy among females and balance disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Tambocor. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,953 Topamax users. Check the latest studies of Topamax.

What is Tambocor?

Tambocor has active ingredients of flecainide acetate. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 2,621 Tambocor users. Check the latest studies of Tambocor.

On Mar, 10, 2026

11 people who take Topamax and Tambocor together, and have interactions are studied.

What are the common drug interactions of Topamax and Tambocor, by gender? *:

female:

Cerebral atrophy (decrement in size of brain)
Dementia (madness)
Hypertension (high blood pressure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abnormal behaviour
Activated partial thromboplastin time prolonged
Areflexia (absence of a reflex)
Balance disorder
Blood sodium decreased
Campylobacter infection (infection by the campylobacter bacterium)

male:

Balance disorder
Confusional state
Somnolence (a state of near-sleep, a strong desire for sleep)
Speech disorder
Vision blurred
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal failure (kidney dysfunction)
Depression
Disorientation (disability in which the senses of time, direction, and recognition of people and places)

What are the common drug interactions of Topamax and Tambocor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abnormal behaviour
Activated partial thromboplastin time prolonged
Areflexia (absence of a reflex)
Balance disorder
Blood sodium decreased
Confusional state
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Demyelination (loss of the myelin covering of some nerve fibres resulting in their impaired function)
Depressed level of consciousness
Drug abuser

30-39:

n/a

40-49:

Campylobacter infection (infection by the campylobacter bacterium)
Clostridium test positive
Influenza

50-59:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Disturbance in attention
Dizziness
Feeling drunk
Memory impairment
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Reading disorder (problem in areas of the brain that help interpret language)
Somnolence (a state of near-sleep, a strong desire for sleep)
Speech disorder
Vision blurred

60+:

Cerebral atrophy (decrement in size of brain)
Dementia (madness)
Hypertension (high blood pressure)
Sepsis (a severe blood infection that can lead to organ failure and death)
Chronic kidney disease
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Neuropathy Peripheral (surface nerve damage): 3 people, 27.27%
Neuralgia (pain in one or more nerves): 3 people, 27.27%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 27.27%
Oedema (fluid collection in tissue): 2 people, 18.18%
Mononeuropathy (a type of damage to nerves outside the brain and spinal cord): 2 people, 18.18%
Hereditary Disorder: 2 people, 18.18%
Sleep Disorder: 1 person, 9.09%
Pain: 1 person, 9.09%
Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 1 person, 9.09%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Topamax and Tambocor?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously