Topamax and Valturna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Valturna (aliskiren hemifumarate; valsartan). Common drug interactions include tendon rupture among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Valturna. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

What is Valturna?

Valturna has active ingredients of aliskiren hemifumarate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 619 Valturna users. Check the latest studies of Valturna.

On Apr, 21, 2026

15 people who take Topamax and Valturna together, and have interactions are studied.

What are the common drug interactions of Topamax and Valturna, by gender? *:

female:

Tendon rupture (tear of tendon)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Contusion (a type of hematoma of tissue in which capillaries)
Fall
Joint injury
Joint swelling
Post procedural infection
Road traffic accident
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Surgery

male:

Anxiety
Asthma
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Swollen tongue (swelling of tongue)
Tardive dyskinesia (a disorder that involves involuntary movements)
Tremor (trembling or shaking movements in one or more parts of your body)
Trismus (reduced opening of the jaws)
Cough
Disturbance in attention
Dysphemia (stammering or stuttering)

What are the common drug interactions of Topamax and Valturna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Contusion (a type of hematoma of tissue in which capillaries)
Fall
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Joint injury
Joint swelling
Post procedural infection
Tendon rupture (tear of tendon)
Surgery
Limb injury
Road traffic accident

60+:

Anaemia (lack of blood)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depression
Dyspnoea (difficult or laboured respiration)
Limb traumatic amputation (loss of leg due to injury)
Nerve injury
Road traffic accident
Tremor (trembling or shaking movements in one or more parts of your body)
Coma (state of unconsciousness lasting more than six hours)
Respiratory disorder (respiratory disease)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 80.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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