Topamax and Vancomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Vancomycin (vancomycin). Common drug interactions include poor venous access among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Vancomycin. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,953 Topamax users. Check the latest studies of Topamax.

What is Vancomycin?

Vancomycin has active ingredients of vancomycin. eHealthMe is studying from 17,165 Vancomycin users. Check the latest studies of Vancomycin.

On Feb, 06, 2026

33 people who take Topamax and Vancomycin together, and have interactions are studied.

Topamax and Vancomycin drug interactions.

What are the common drug interactions of Topamax and Vancomycin, by gender? *:

female:

Poor venous access
Sialoadenitis (inflammation of a salivary gland)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Urinary tract infection
Vertigo
Vitamin d deficiency
Chronic kidney disease
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Somnolence (a state of near-sleep, a strong desire for sleep)
Renal failure (kidney dysfunction)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Decreased activity
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Disseminated intravascular coagulation (systemic activation of blood coagulation)
Drug ineffective
Emotional distress
Gait disturbance
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

What are the common drug interactions of Topamax and Vancomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Disseminated intravascular coagulation (systemic activation of blood coagulation)
Multiple-drug resistance
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Thrombocytopenia (decrease of platelets in blood)

20-29:

Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cough
Crying
Depressed level of consciousness
Device failure
Drug hypersensitivity
Drug ineffective
Influenza
Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
Nephrolithiasis (calculi in the kidneys)

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Acute left ventricular failure (heart attack)
Acute respiratory failure
Agitation (state of anxiety or nervous excitement)
Depression
Hospitalisation
Nephrogenic anaemia (anaemia due to kidney disease)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

40-49:

Asthenia (weakness)
Confusional state
Hypotension (abnormally low blood pressure)
Pneumonia
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Somnolence (a state of near-sleep, a strong desire for sleep)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Food allergy
Back disorder
Back pain

50-59:

Chronic kidney disease
Decreased activity
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Emotional distress
Gait disturbance
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Intervertebral disc protrusion (spinal disc protrusion)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Mobility decreased (ability to move is reduced)

60+:

Hallucination (an experience involving the perception of something not present)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 42.42%
Pain: 8 people, 24.24%
Infection: 5 people, 15.15%
Immunodeficiency Common Variable: 5 people, 15.15%
Combined Immunodeficiency: 5 people, 15.15%
High Blood Cholesterol: 5 people, 15.15%
Asthma: 4 people, 12.12%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 12.12%
High Blood Pressure: 4 people, 12.12%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 12.12%

* Approximation only. Some reports may have incomplete information.

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