Topamax and Withania drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topamax (topiramate) and Withania (ashwagandha). Common drug interactions include alopecia among females and insomnia among males.

The phase IV clinical study analyzes what interactions people have when they take Topamax and Withania. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

What is Withania?

Withania has active ingredients of ashwagandha. eHealthMe is studying from 391 Withania users. Check the latest studies of Withania.

On Jul, 19, 2026

11 people who take Topamax and Withania together, and have interactions are studied.

What are the common drug interactions of Topamax and Withania, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Sedation
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blood pressure increased
Cough
Insomnia (sleeplessness)
Nephrolithiasis (calculi in the kidneys)
Psoriasis (immune-mediated disease that affects the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Seasonal allergy (allergic condition due to certain season)

male:

Insomnia (sleeplessness)

What are the common drug interactions of Topamax and Withania, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Alopecia (absence of hair from areas of the body)
Seasonal allergy (allergic condition due to certain season)
Visual impairment
Vitamin b complex deficiency
Weight increased
Inflammation
Sinusitis (inflammation of sinus)
Blood pressure fluctuation
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Sedation

60+:

Insomnia (sleeplessness)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 81.82%
Pain: 2 people, 18.18%
Stress And Anxiety: 1 person, 9.09%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 9.09%
Seasonal Allergy (allergic condition due to certain season): 1 person, 9.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 9.09%
Movement - Uncontrolled Or Slow: 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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