Topiramate and Tazidime drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Topiramate (topiramate) and Tazidime (ceftazidime). Common drug interactions include adult respiratory distress syndrome among females and dystonia among males.
The phase IV clinical study analyzes what interactions people have when they take Topiramate and Tazidime. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Topiramate?
Topiramate has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 49,809 Topiramate users. Check the latest studies of Topiramate.
What is Tazidime?
Tazidime has active ingredients of ceftazidime. eHealthMe is studying from 10,409 Tazidime users. Check the latest studies of Tazidime.
13 people who take Topiramate and Tazidime together, and have interactions are studied.

What are the common drug interactions of Topiramate and Tazidime, by gender? *:
female:
- Adult respiratory distress syndrome (type of lung (pulmonary) failure)
- Pyrexia (fever)
- Rash erythematous (redness of the skin)
- Rash papular (redness with papule)
- Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Anxiety
- Blood creatinine increased
- Depression
- Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
- Dermatitis lichenoid (lichen simplex chronicus is a chronic inflammation of the skin)
male:
- Dystonia (abnormal muscle tone)
What are the common drug interactions of Topiramate and Tazidime, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
- Drug ineffective
- Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
20-29:
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Decreased appetite
- Nausea (feeling of having an urge to vomit)
- Ventricular fibrillation (abnormally irregular heart rhythm)
30-39:
- Anxiety
- Blood creatinine increased
- Chronic kidney disease
- Depression
- Renal injury (kidney injury)
40-49:
- Chronic kidney disease
50-59:
- Dystonia (abnormal muscle tone)
- Nephrolithiasis (calculi in the kidneys)
- Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
60+:
- Adult respiratory distress syndrome (type of lung (pulmonary) failure)
- Coma (state of unconsciousness lasting more than six hours)
- Rash papular (redness with papule)
- Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Dermatitis lichenoid (lichen simplex chronicus is a chronic inflammation of the skin)
- Granuloma (a small area of inflammation due to tissue injury)
- Heart rate increased
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters)
- Platelet count decreased
What are the existing conditions these people have? *
- Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 2 people, 15.38%
- Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 15.38%
- Diabetes: 2 people, 15.38%
- High Blood Pressure: 2 people, 15.38%
- Hiv Infection: 2 people, 15.38%
- Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 2 people, 15.38%
- Wound Infection Pseudomonas: 1 person, 7.69%
- Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 1 person, 7.69%
- Asthma: 1 person, 7.69%
- Back Pain: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Topiramate and Tazidime?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Topiramate (49,809 reports)
- Tazidime (10,409 reports)
Browse all drug interactions of Topiramate and Tazidime:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Topiramate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tazidime:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Topiramate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tazidime and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Chen F, Zhan Z, "Severe drug-induced immune haemolytic anaemia due to ceftazidime", Blood Transfusion, 2014 Jan .
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
- Chen F, Zhan Z, "Severe drug-induced immune haemolytic anaemia due to ceftazidime", Blood Transfusion, 2014 Jan .
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on topiramate and ceftazidime (the active ingredients of Topiramate and Tazidime, respectively), and Topiramate and Tazidime (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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