Topiramate and Testosterone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topiramate (topiramate) and Testosterone (testosterone). Common drug interactions include paraesthesia among females and infection among males.

The phase IV clinical study analyzes what interactions people have when they take Topiramate and Testosterone. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Topiramate?

Topiramate has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 49,809 Topiramate users. Check the latest studies of Topiramate.

What is Testosterone?

Testosterone has active ingredients of testosterone. It is often used in testosterone. eHealthMe is studying from 6,457 Testosterone users. Check the latest studies of Testosterone.

On Aug, 08, 2026

52 people who take Topiramate and Testosterone together, and have interactions are studied.

Topiramate and Testosterone drug interactions.

What are the common drug interactions of Topiramate and Testosterone, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Productive cough
Rash pruritic (redness with itching)
Respiratory tract congestion (blockage on respiratory system)
Rhinorrhoea (watery mucus discharge from the nose)
Upper respiratory tract infection
Renal impairment (severely reduced kidney function)
Asthma

male:

Infection
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Blood creatine phosphokinase increased
Blood pressure increased
Completed suicide (act of taking one's own life)
Enuresis (repeated inability to control urination)
Haematochezia (passage of stools containing blood)
Hepatic steatosis (fatty liver disease)
Hypersomnia (excessive daytime sleepiness (eds))
Hypotension (abnormally low blood pressure)

What are the common drug interactions of Topiramate and Testosterone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Weight decreased
Idiopathic intracranial hypertension (elevated cerebrospinal fluid pressure of unknown cause)
Papilloedema (optic disc swelling)
Somnolence (a state of near-sleep, a strong desire for sleep)
Visual field defect

20-29:

Completed suicide (act of taking one's own life)
Drug ineffective
Suicidal ideation
Chronic kidney disease
Hypertension (high blood pressure)
Hypertensive crisis
Palpitations (feelings or sensations that your heart is pounding or racing)

30-39:

Blindness
Intraocular pressure increased
Lens dislocation
Night blindness (inability to see in night as day)
Vision blurred

40-49:

Somnolence (a state of near-sleep, a strong desire for sleep)
Asthma
Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Blood cholesterol increased
Blood creatine phosphokinase increased
Chest pain
Enuresis (repeated inability to control urination)
Haematochezia (passage of stools containing blood)
Hepatic steatosis (fatty liver disease)
Hypersomnia (excessive daytime sleepiness (eds))

50-59:

Paranasal sinus discomfort
Physical assault
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Pruritus (severe itching of the skin)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Road traffic accident
Sinus disorder (disease of sinus)
Sinusitis (inflammation of sinus)

60+:

Weight increased
Bruxism (habitual grinding of the teeth, typically during sleep)
Neck pain
Nephrolithiasis (calculi in the kidneys)
Oedema (fluid collection in tissue)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Productive cough
Rash pruritic (redness with itching)

What are the existing conditions these people have? *

Pain: 7 people, 13.46%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 13.46%
Stress And Anxiety: 7 people, 13.46%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 11.54%
High Blood Pressure: 6 people, 11.54%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 9.62%
Depression: 5 people, 9.62%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 9.62%
Blood Testosterone Decreased: 4 people, 7.69%
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 4 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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