Topotecan and Diovan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Topotecan (topotecan hydrochloride) and Diovan (valsartan). Common drug interactions include interstitial lung disease among females and anaphylactoid reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Topotecan and Diovan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Topotecan?

Topotecan has active ingredients of topotecan hydrochloride. eHealthMe is studying from 5,853 Topotecan users. Check the latest studies of Topotecan.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. eHealthMe is studying from 83,153 Diovan users. Check the latest studies of Diovan.

On Jul, 11, 2026

18 people who take Topotecan and Diovan together, and have interactions are studied.

What are the common drug interactions of Topotecan and Diovan, by gender? *:

female:

Interstitial lung disease
Cardiac failure congestive
Respiratory failure (inadequate gas exchange by the respiratory system)
Anaemia (lack of blood)
Dry skin
White blood cell count decreased
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Electrolyte imbalance
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

male:

Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Congestive cardiomyopathy (weakening of heart muscle)
Bronchopleural fistula
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Cough
Disease progression
Dry skin
Hepatic enzyme increased
Hyperglycaemia (high blood sugar)
Hypoaesthesia (reduced sense of touch or sensation)

What are the common drug interactions of Topotecan and Diovan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Interstitial lung disease
Cardiac failure congestive
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
Renal failure acute (rapid kidney dysfunction)
Lung neoplasm malignant (cancer tumour of lung)
Blood calcium decreased
Bone pain
Bronchopleural fistula
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 6 people, 33.33%
Upper Respiratory Tract Infection: 5 people, 27.78%
Respiratory Tract Congestion (blockage on respiratory system): 5 people, 27.78%
Colon Cancer: 4 people, 22.22%
Diabetes: 3 people, 16.67%
Rectal Cancer Metastatic (cancer of rectum spreads to other): 2 people, 11.11%
Enlarged Prostate: 2 people, 11.11%
Vestibular Neuronitis (inflammation of the vestibular nerve): 1 person, 5.56%
Endometrial Cancer: 1 person, 5.56%
Cancer Pain: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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