Toradol and Ritalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Toradol (ketorolac tromethamine) and Ritalin (methylphenidate hydrochloride). Common drug interactions include headache among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Toradol and Ritalin. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Toradol?

Toradol has active ingredients of ketorolac tromethamine. It is often used in pain. eHealthMe is studying from 9,230 Toradol users. Check the latest studies of Toradol.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

On Jul, 13, 2026

52 people who take Toradol and Ritalin together, and have interactions are studied.

What are the common drug interactions of Toradol and Ritalin, by gender? *:

female:

Headache (pain in head)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Vertigo
Dizziness
Hypokalaemia (low potassium)
Injury
Insomnia (sleeplessness)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Metastases to bone (cancer spreads to bone)

male:

Headache (pain in head)
Anxiety
Delirium (wild excitement)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hepatic failure (liver failure)
Renal failure (kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Soft tissue injury
Gait disturbance

What are the common drug interactions of Toradol and Ritalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anaemia (lack of blood)
Gastric ulcer (stomach ulcer)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

20-29:

Vertigo
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
Adenoma benign (non-cancerous tumour -secreting)
Adnexa uteri cyst (ovarian cysts)
Allergic sinusitis
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic calcification (aortic calcification sign of heart valve disease)
Aortic valve sclerosis (narrowing of the aortic valve)
Arthralgia (joint pain)

30-39:

Intervertebral disc protrusion (spinal disc protrusion)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Abdominal discomfort
Abdominal pain
Alanine aminotransferase increased
Anxiety
Aspartate aminotransferase increased
Blood pressure decreased
Cellulitis (infection under the skin)
Chills (felling of cold)

40-49:

Memory impairment
Abdominal pain upper
Anxiety
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)
Chills (felling of cold)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)

50-59:

Cough
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug ineffective
Insomnia (sleeplessness)
Irritable bowel syndrome
Restless legs syndrome (a powerful urge to move your legs)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Malignant neoplasm progression (cancer tumour came back)
Adjustment disorder with depressed mood

60+:

Anxiety
Asthenia (weakness)
Injury
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Metastases to bone (cancer spreads to bone)
Nausea (feeling of having an urge to vomit)
Osteonecrosis of jaw (death of bone of jaw)
Pleural fibrosis (formation of fibrous tissue in lung)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Vertigo

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 23.08%
Metastases To Bone (cancer spreads to bone): 12 people, 23.08%
Insomnia (sleeplessness): 11 people, 21.15%
Depression: 11 people, 21.15%
Osteoporosis (bones weak and more likely to break): 9 people, 17.31%
Neoplasm Malignant (cancer tumour): 9 people, 17.31%
Muscle Spasms (muscle contraction): 6 people, 11.54%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 11.54%
White Blood Cell Count Increased: 5 people, 9.62%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 9.62%

* Approximation only. Some reports may have incomplete information.

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