Torisel and Megace drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Torisel (temsirolimus) and Megace (megestrol acetate). Common drug interactions include lip swelling among females and anaemia among males.
The phase IV clinical study analyzes what interactions people have when they take Torisel and Megace. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Torisel?
Torisel has active ingredients of temsirolimus. eHealthMe is studying from 3,205 Torisel users. Check the latest studies of Torisel.
What is Megace?
Megace has active ingredients of megestrol acetate. It is often used in weight loss. eHealthMe is studying from 10,095 Megace users. Check the latest studies of Megace.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
16 people who take Torisel and Megace together, and have interactions are studied.

What are the common drug interactions of Torisel and Megace, by gender? *:
female:
- Lip swelling
male:
- Anaemia (lack of blood)
- Dehydration (dryness resulting from the removal of water)
- Bone disorder
- Cellulitis (infection under the skin)
- Chest discomfort
- Disease progression
- Drug hypersensitivity
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Feeling cold
What are the common drug interactions of Torisel and Megace, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Lip swelling
50-59:
- Anaemia (lack of blood)
- Nausea (feeling of having an urge to vomit)
- Pain
- Pneumonia
- Renal failure (kidney dysfunction)
- Bone disorder
- Dehydration (dryness resulting from the removal of water)
- Drug hypersensitivity
- Fatigue (feeling of tiredness)
- Lung neoplasm (tumour of lung)
60+:
- Cellulitis (infection under the skin)
- Chest discomfort
- Renal cell carcinoma (a kidney cancer)
- Swelling
- Disease progression
- Dyspnoea (difficult or laboured respiration)
- Feeling cold
- Mouth ulceration (mouth ulcers)
- Mucosal inflammation (infection of mucous membrane)
- Pleural effusion (water on the lungs)
What are the existing conditions these people have? *
- Prostate Cancer: 6 people, 37.50%
- Renal Cell Carcinoma Stage Unspecified (kidney cancer in unknown stage): 4 people, 25.00%
- Pain: 4 people, 25.00%
- Renal Cell Carcinoma (a kidney cancer): 3 people, 18.75%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 3 people, 18.75%
- Neuralgia (pain in one or more nerves): 1 person, 6.25%
- Nausea (feeling of having an urge to vomit): 1 person, 6.25%
- Metastasis (spreadable cancer to other organ from origin): 1 person, 6.25%
- High Blood Pressure: 1 person, 6.25%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Torisel and Megace?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Torisel and Megace:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Torisel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Megace:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Torisel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Megace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Herrin MA, Rubinstein JC, Christison-Lagay ER, "Temsirolimus therapy and small bowel perforation in a pediatric patient with Clostridium septicum bacteremia", Journal of Pediatric Surgery Case Reports, 2015 Aug .
- Herrin MA, Rubinstein JC, Christison-Lagay ER, "Temsirolimus therapy and small bowel perforation in a pediatric patient with Clostridium septicum bacteremia", Journal of Pediatric Surgery Case Reports, 2015 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on temsirolimus and megestrol acetate (the active ingredients of Torisel and Megace, respectively), and Torisel and Megace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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